Purpose: To identify the main indications for corneal transplantation, analyze the results and provide demographic and epidemiological profile of patients referred to the Corneal Transplantation Project.
Methods: A retrospective analysis, from June to December 2003, of patients referred to the Corneal Transplantation Project.
Results: Total of 171 patients. One hundred and two (59.6%) patients were male and 69 (40.3%) female; mean age was 37 years. One hundred and six (49%) patients had indication for corneal transplantation. The origins of patients were: São Paulo (68%), Minas Gerais (6%), Paraná (6%), Rio de Janeiro (5%), Maranhão (3%) and others (12%). The main indications: keratoconus 65%, pseudophakic bullous keratopathy 21%, corneal scarring 10%, Fuchs dystrophy 1.9%, lattice dystrophy 0.9% and Stevens-Johnson syndrome 0.9%.
Conclusion: Many patients referred to corneal transplantation had no indication for such procedure. This fact demonstrates the poor knowledge of general ophthalmologists about the real indications of penetrating keratoplasty. Keratoconus was the major indication followed by pseudophakic bullous keratopathy.
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http://dx.doi.org/10.1590/s0004-27492006000500007 | DOI Listing |
Front Med (Lausanne)
January 2025
Dalian Medical University, Dalian, China.
Background: The study aimed to review the etiology of corneal blindness and investigate the relative risk of corneal graft rejection (CGR) in the southern Liaoning region.
Methods: The clinical records of 359 patients (394 eyes) who underwent corneal transplantation at the Department of Keratoconus of the Third People's Hospital of Dalian from January 2019 to December 2023 were retrospectively analyzed. The data included patients' age, gender, occupation, diagnosis, surgical procedure, postoperative immune rejection, and neovascularization.
BMC Ophthalmol
January 2025
Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Kargar Street, Tehran, Iran.
Purpose: To analyze the outcomes of corneal transplantation procedures over a 13-year period at Farabi Eye Hospital, Tehran, Iran, to identify trends and determinants influencing the frequency and success of primary and re-transplantations.
Methods: Utilizing a comprehensive dataset from the hospital's Hospital Information System, the study reviewed the records of 8,378 patients who underwent corneal transplants between 2009 and 2022. This analysis included demographic information, surgical details, and follow-up data.
Drugs
January 2025
Moorfields Eye Hospital, 162 City Road, London, EC1V 2PD, UK.
Neurotrophic keratitis is a rare eye condition characterised by reduced or absent corneal sensation. This leads to impaired corneal healing through a loss of protective mechanisms such as blinking. The cornea becomes vulnerable to persistent epithelial defects, ulceration, infection and ultimately, vision loss or loss of the eye.
View Article and Find Full Text PDFInt J Pharm
January 2025
National Engineering Research Center of Ophthalmology and Optometry, School of Biomedical Engineering, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027 China. Electronic address:
Maintaining the clarity of the cornea is crucial for optimal vision. Corneal scarring (CS), resulting from corneal inflammation, trauma, or surgery, can lead to a reduction in corneal transparency and visual impairment. While corneal transplantation is the primary method for restoring vision, the limited availability of corneal donor presents a significant challenge on a global scale.
View Article and Find Full Text PDFCornea
January 2025
Department of Ophthalmology, Illinois Eye and Ear Infirmary, University of Illinois, Chicago, IL; and.
Purpose: To report the indications, postoperative visual outcomes, and long-term graft survival of primary pediatric keratoplasties performed at a single tertiary care center.
Methods: We conducted a retrospective review of pediatric patients (16 years and younger) who underwent surgical intervention for corneal opacity at a tertiary care center to evaluate long-term graft survival and visual rehabilitation.
Results: Seventy-three eyes of 46 patients met inclusion criteria.
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