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Combination drug therapy prevents CIAKI by suppressing ER stress-induced apoptosis.
Sci Rep
December 2024
Department of Cardiology, Tianjin Chest Hospital, No. 261 of Taierzhuang South Road, Tianjin, 300121, China.
Contrast-induced acute kidney injury (CIAKI) is an important clinical complication that occurs after the application of contrast agent in percutaneous coronary intervention. The pathogenesis of CIAKI is complex. Studies have shown that cell apoptosis induced by endoplasmic reticulum stress (ERS) plays an important role in renal tubular injury in CIAKI.
View Article and Find Full Text PDFTherapeutic management of erectile dysfunction: the AFU/SFMS guidelines.
Fr J Urol
December 2024
Department of Urology, Hospital of Monaco, France.
Context: Erectile dysfunction (ED) is a common sexual disorder. In France, recent evidence-based guidelines are lacking.
Aim: To provide practice guidelines on ED therapeutic management.
A Retrospective Review of Men Referred to a Dedicated Erectile Dysfunction Clinic in Secondary Care.
Cureus
June 2024
Urology, Cwm Taf University Health Board, Royal Glamorgan Hospital, Cardiff, GBR.
Background and objectives Erectile dysfunction (ED) is a multifactorial disease associated with many medical co-morbidities and risk factors commonly encountered in primary care. Initial management includes lifestyle changes and the treatment of any identifiable conditions. Guidelines exist recommending the assessment and management of sufferers with clear indications for referral to secondary care.
View Article and Find Full Text PDFAssociation between Postoperative Adjuvant Vasodilator Therapy and In-Hospital Mortality for Non-Occlusive Mesenteric Ischemia: A Nationwide Observational Study.
J Nippon Med Sch
July 2024
Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo.
Article Synopsis
- A study analyzed the effectiveness of postoperative vasodilator therapy for patients with non-occlusive mesenteric ischemia (NOMI) using data from a large Japanese inpatient database between 2010 and 2018.
- The research involved comparing outcomes between patients who received vasodilators and those who did not, focusing on in-hospital mortality and additional surgeries.
- Results showed no significant differences in mortality rates or the need for further surgery between the two groups, indicating vasodilator therapy may not improve outcomes for NOMI patients after surgery.
Patient out-of-pocket costs for guideline-recommended treatments for erectile dysfunction: a medicare cost modeling analysis.
Int J Impot Res
January 2025
Department of Urology, UC San Diego Health, San Diego, CA, USA.
Patient out-of-pocket (OOP) cost represents an access barrier to erectile dysfunction (ED) treatment. We determined OOP cost for men with ED covered by Fee-for-Service Medicare. Coverage policies were obtained from the Medicare Coverage Database for treatments recommended by the 2018 American Urological Association (AUA) guidelines.
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