Objective: The present study investigated the behavioral patterns of autistic children during infancy to provide clues for early identification of childhood autism.
Methods: The abnormal behaviors of 30 children with autism and 26 children with other developmental disorders in infancy were investigated.
Results: The children with autism presented a series of abnormal behaviors, including no social smile, no eye contact and no respond to own name, and joint attention deficiency, which were distinguished from the children with other developmental disorders. The imitation and attachment behaviors were significantly different between the two groups. Repetitive motor actions and interest peculiarity were only seen in children with autism.
Conclusions: The children with autism may present a series of abnormal behaviors as early as in infancy. The abnormal behaviors facilitate early diagnosis of autism.
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Viruses
December 2024
Department of Research, Altino Ventura Foundation (FAV), Recife 50070-040, Brazil.
Deformities, body asymmetries, and muscle contractures are common consequences of atypical postural patterns in children with c ongenital Zika syndrome (CZS). This study aimed to evaluate the posture of children with CZS, considering their neurological and visual impairments. Ophthalmological assessment included binocular best-corrected visual acuity (BCVA) using Teller Acuity Cards II (TAC II) and an ocular motility evaluation.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Division of Computer Science & Artificial Intelligence, Dongguk University, Seoul 04620, Republic of Korea.
Anomaly detection is critical in safety-sensitive fields, but faces challenges from scarce abnormal data and costly expert labeling. Time series anomaly detection is relatively challenging due to its reliance on sequential data, which imposes high computational and memory costs. In particular, it is often composed of real-time collected data that tends to be noisy, making preprocessing an essential step.
View Article and Find Full Text PDFNutrients
December 2024
School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.
Few studies have explored the links between adiposity, metabolic health, and lung function. This study examined the cross-sectional association between spirometric lung function and overweight/obesity, with and without metabolic abnormalities, in older adults. The research involved 3,318 older adults from the Hunter Community Study Cohort who had a BMI of 18.
View Article and Find Full Text PDFPharmaceuticals (Basel)
December 2024
School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Background: Durazz. is one of the most popular herbs used for depression treatment, but the molecular basis for its mechanism of action has not been fully addressed. Previously, we isolated and identified two lignan glycoside derivatives that were shown to noncompetitively inhibit serotonin transporter (SERT) activity but with a relatively low inhibitory potency compared with those of conventional antidepressants.
View Article and Find Full Text PDFMolecules
December 2024
Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine Kohnodai Hospital, 1-7-1 Kohnodai, Ichikawa 272-8516, Chiba, Japan.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with cognitive dysfunction, memory decline, and behavioral disturbance, and it is pathologically characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain. Although various hypotheses have been proposed to explain the pathogenesis of AD, including the amyloid beta hypothesis, oxidative stress hypothesis, and abnormal phosphorylation of tau proteins, the exact pathogenic mechanisms underlying AD remain largely undefined. Furthermore, effective curative treatments are very limited.
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