Contemporary drug policy in the United States favors a balanced approach including a supply side dimension. The supply side dimension is grounded in the assumption that the disruption of illicit drug markets will result in diminished capacity of the markets to provide for consumer demand and thereby a reduction in the use of illicit drugs and a related increase in demand for treatment. In this paper we consider the disruption of methamphetamine markets in 10 cities in terms of the relative stability of those markets. We use data from the Arrestee Drug Abuse Monitoring (ADAM) program for the years 2000-2003. We conduct a comparative analysis of those markets and look at patterns of methamphetamine use and participation in treatment in those cities. Our findings demonstrate how it is possible to construct measures of market stability, and how to use those measures to assess the stability of illicit drug markets in terms of both relative value and in fluctuation over time. We also demonstrate that markets with different patterns of stability will exhibit different patterns of drug using and treatment participation. We conclude that understanding patterns of market stability will help us to understand and respond to patterns of drug using and treatment participation.
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http://dx.doi.org/10.1016/j.drugalcdep.2006.11.010 | DOI Listing |
Int J Drug Policy
December 2024
Instituto do Mar, Universidade Federal de São Paulo (UNIFESP), Santos, Brazil.
Background: Illicit cigarette consumption (ICC) results in cheaper cigarettes and lost tax revenue. Although several methods estimate the ICC proportion, the one based on cigarette butt (CB), the most littered item worldwide, is less common. This study aimed at estimating the ICC proportion of Guarujá, a major Brazilian city, based on littered CBs.
View Article and Find Full Text PDFAm J Emerg Med
December 2024
Icahn School of Medicine at Mount Sinai, Center for Research on Emerging Substances, Poisoning, Overdose, and New Discoveries (RESPOND), NYC Health + Hospitals/Elmhurst, New York, NY, USA.
Background: Tramadol is an adulterant of illicit opioids. As it is a serotonin-norepinephrine reuptake inhibitor as well as a μ-opioid agonist, tramadol adulteration may worsen overdose signs and symptoms or affect the amount of naloxone patients receive.
Methods: This is a multicenter, prospective cohort of adult patients with suspected opioid overdoses who presented to one of eight United States emergency departments and were included in the Toxicology Investigators Consortium's Fentalog Study.
Future Med Chem
December 2024
Centre for Drug and Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Methamphetamine (METH) is a highly addictive illicit psychostimulant with a significant annual fatality rate. Emerging studies highlight its role in neuroinflammation and a range of neurological disorders. This review examines the current landscape of potential drug targets for managing neuroinflammation in METH use disorders (MUDs), with a particular focus on the rationale behind targeting Toll-like receptor 4 (TLR4), the NLR family pyrin domain containing 3 (NLRP3) inflammasome, and other promising targets.
View Article and Find Full Text PDFCongenit Anom (Kyoto)
December 2024
Center for Registry and Research in Congenital Anomalies (CRIAC), Service of Genetics and Cytogenetics Unit, Pediatrics Division, "Dr. Juan I. Menchaca" Civil Hospital of Guadalajara, Guadalajara, Jalisco, Mexico.
Congenital heart defects (CHDs) are caused by a complex interaction between numerous genetic and environmental risk factors, some of which may differ between different populations. A case-control study was conducted among 1232 newborns, including 308 patients with isolated CHDs (cases) and 924 infants without birth defects (controls), born all during the period 2009-2023 at the Hospital Civil de Guadalajara "Dr. Juan I.
View Article and Find Full Text PDFHealth Promot J Austr
January 2025
Health Behaviour Research Collaborative, School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
Issue Addressed: Smoking rates have been steadily declining among Aboriginal and Torres Strait Islander people. Examining the factors associated with not smoking in young people is crucial for understanding the motivations and influences that lead individuals to adopt healthy behaviours.
Methods: Secondary analysis was undertaken of data collected as part of the National Aboriginal and Torres Strait Islander Social Survey (NATSISS) 2014-15 (n = 1456).
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