Objective: To relate the symptoms of benign prostate hyperplasia (BPH) to their repercussions on quality of life.
Design: Multi-centred, observational, prospective study.
Setting: Primary care.
Participants: Men with BPH in 2000-2003. Inclusion criteria were: agreeing to take part, being aged 50-79, and having moderate symptoms evaluated by means of the IPSS questionnaire.
Exclusion Criteria: Previous treatment for BPH and having a chronic or disabling illness that might affect perception of quality of life. The presence of irritative and obstructive symptoms was appraised.
Main Measurements: The IPSS questionnaire appraising predominant symptoms and, through the last question, quality of life was self-administered. Descriptive statistics were worked out and differences in proportions of the different groups were analysed by the chi2 test, with differences taken as significant at P < .05.
Results: We got 536 replies, with average age 66.2. Nycturia was the most common symptom, suffered by 88.1% of patients. A total of 256 patients (47.8%) had irritation as main clinical symptom, and 280 (52.2%), obstruction. On analysing repercussions on quality of life, it was found that obstructive symptoms were worse tolerated: 65.7% versus 9.4% of the group with irritation.
Conclusions: In treating BPH, we must bear in mind preferences of patients. They tolerate obstructive symptoms worse, and these are a criterion for referral to specialists and even surgery.
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http://dx.doi.org/10.1016/s0212-6567(06)70530-3 | DOI Listing |
JMIR Form Res
January 2025
Department of Computer Science, University Hospital of Geneva, Geneva, Switzerland.
Background: Mobile health apps have shown promising results in improving self-management of several chronic diseases in patients. We have developed a mobile health app (Cardiomeds) dedicated to patients with heart failure (HF). This app includes an interactive medication list; daily self-monitoring of symptoms, weight, blood pressure, and heart rate; and educational information on HF delivered through various formats.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
Importance: Mental health issues among young people are increasingly concerning. Conventional psychological interventions face challenges, including limited staffing, time commitment, and low completion rates.
Objective: To evaluate the effect of a low-intensity online intervention on young people in Hong Kong experiencing moderate or greater mental distress.
J Speech Lang Hear Res
January 2025
Centre for Language Studies, Radboud University, Nijmegen, the Netherlands.
Purpose: In this review article, we present an extensive overview of recent developments in the area of dysarthric speech research. One of the key objectives of speech technology research is to improve the quality of life of its users, as evidenced by the focus of current research trends on creating inclusive conversational interfaces that cater to pathological speech, out of which dysarthric speech is an important example. Applications of speech technology research for dysarthric speech demand a clear understanding of the acoustics of dysarthric speech as well as of speech technologies, including machine learning and deep neural networks for speech processing.
View Article and Find Full Text PDFPain Ther
January 2025
Robert Wood Johnson University Hospital/Rutgers Medical School, New Brunswick, NJ, USA.
Introduction: Many interventional strategies are commonly used to treat chronic low back pain (CLBP), though few are specifically intended to target the distinct underlying pathomechanisms causing low back pain. Restorative neurostimulation has been suggested as a specific treatment for mechanical CLBP resulting from multifidus dysfunction. In this randomized controlled trial, we report outcomes from a cohort of patients with CLBP associated with multifidus dysfunction treated with restorative neurostimulation compared to those randomized to a control group receiving optimal medical management (OMM) over 1 year.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
January 2025
Medical Affairs, Otsuka Pharmaceutical Co., Ltd., Shinagawa Grand Central Tower, 2-16-4 Konan, Minato-ku, Tokyo, 108-8241, Japan.
Introduction: The impact of atopic dermatitis (AD) on daily life and different levels of quality of life (QOL) according to AD severity has not been fully elucidated. This study aimed to assess QOL in relation to the AD severity in Japan.
Methods: This observational study used anonymized data of health insurance association members and their families registered to a mobile health app.
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