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Introduction: Giant omphalocele poses a conflict between eviscerated content and abdominal capacity, with associated risks such as compartment syndrome or cardiovascular compromise.
Clinical Case: We present the case of a prenatally diagnosed hepato-omphalocele, without associated abnormalities. At week 37, botulinum toxin was injected in the right hemiabdomen under fetal and maternal sedation.
Intracoronary Tissue Plasminogen Activator Therapy to Treat Thrombotic Occlusion of a Giant Coronary Aneurysm in Early Kawasaki Disease.
Catheter Cardiovasc Interv
December 2024
Department of Fetal, Neonatal and Cardiovascular Sciences, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Kawasaki Disease (KD) is a systemic vasculitis that can lead to coronary artery aneurysms (CAA) in up to 10% of treated cases, significantly increasing the risk of thrombosis and acute myocardial infarction (AMI). While thrombolytic therapy is commonly used in adult coronary syndromes, its application in pediatric KD remains poorly studied. We report a 9-month-old infant with KD and giant CAA complicated by a subocclusive thrombus in the left anterior descending artery (LAD).
View Article and Find Full Text PDFFœtal sacrococcygeal teratoma type I: A case report.
Radiol Case Rep
February 2025
Pediatric Surgery Department, Tunis Faculty of Medicine El Manar University, Béchir Hamza Children's Hospital, Tunis, Tunisia.
Sacrococcygeal teratoma (SCT) is a rare congenital tumor typically diagnosed in neonates, with management challenges arising from the size of the tumor and associated delivery complications. In this case, a 32-year-old gravida 5 para 5 woman with a history of three prior cesarean sections was diagnosed with a giant type I SCT at 30 weeks of gestation through prenatal ultrasound, confirmed by fetal MRI. At 34 weeks, an emergency cesarean section was performed due to acute fetal distress, resulting in a newborn with transient respiratory distress.
View Article and Find Full Text PDFEvaluation of expression of amino acid and fatty acid metabolic transporters in the placenta of pregnant women with glucose intolerance.
J Obstet Gynaecol Res
January 2025
Department of Environmental Health, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Article Synopsis
- The study aimed to investigate why pregnant women with glucose intolerance often have large infants, focusing on amino and fatty acid transport in the placenta, beyond just glucose transport.
- Researchers analyzed postpartum placental tissues from 101 eligible deliveries, finding higher expression levels of certain transporters (LAT1 and placenta-FABPpm) in women with glucose intolerance compared to those without.
- The results suggest that, despite controlled blood sugar levels, managing other nutrients like amino acids and fatty acids in glucose-intolerant pregnancies is crucial for fetal growth.
A giant parathyroid cyst causing primary hyperparathyroidism in a pregnant woman: Case report and literature review.
Obstet Med
May 2024
Department of Medicine, School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru.
Introduction: Primary hyperparathyroidism (PHPT) during pregnancy is rare, with the commonest cause being parathyroid adenoma. Parathyroid cysts represent 0.5% of parathyroid lesions.
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