This Perspective provides an overview of the progress in two of the original programs in my research group focused on the biosynthesis of the antibiotics nisin, lacticin 481, fosfomycin, and bialaphos. The path from start-up funds to tenure and beyond offers insights into the opportunities realized and missed along the road.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519235 | PMC |
| http://dx.doi.org/10.1021/jo0614240 | DOI Listing |
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α/β Conflicting Aromaticity Under the Microscope: Study of Pro-Aromatic Radicals.
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University of Vigo, Dept. of Physical Chemistry, Lagoas-Marcosende, 36310, Vigo, SPAIN.
The aromaticity of a representative sample of pro-aromatic radicals and its nitro, amino, hydroxyl and imine substituted derivatives has been analysed by means of multicentre delocalization indices (MCI) and nuclear-independent chemical shifts (NICS). Because of their radical character, these compounds may exhibit conflicting α/ß aromaticity, so that the contribution of α and β electrons to the MCI and NICS has been analysed separately and their values qualitatively interpreted in terms of the 2n+1/2n rule. All the monocyclic radicals investigated show conflicting α/β aromaticity.
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Environ Res
January 2025
Ministry of Ecology and Environment South China Institute of Environmental Sciences, Guangzhou 510655, China; Key Laboratory of Water Environmental Simulation and Pollution Control, Ministry of Ecology and Environment, Guangzhou 510655, China. Electronic address:
Iron-activated peroxyacetic acid (PAA) represents an innovative advanced oxidation process (AOP). However, the efficiency of PAA activation by Fe(III) is often underestimated due to the widespread assumption that Fe(III) exhibits much lower ability than Fe(II) to activate PAA. Herein, the oxidative degradation of Rhodamine B (RhB) by Fe(III)-activated PAA process was investigated, and some new insights into the performance and mechanism of the Fe(III)/PAA system were presented.
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View Article and Find Full Text PDFCarbon-carbon bond formation and cleavage at redox active bis(pyridylimino)isoindole (BPI) germylene compounds.
Dalton Trans
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Instituto de Investigaciones Químicas (IIQ), Departamento de Química Inorgánica, Facultad de Química, and Centro de Innovación en Química Avanzada (ORFEO-CINQA), Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Sevilla, 41092 Sevilla, Spain.
Redox-active ligands provide alternative reaction pathways by facilitating redox events. Among these, tridentate bis(piridylimino)isoindole (BPI) fragments offer great potential, though their redox-active behaviour remains largely underdeveloped. We describe herein a family of BPI germanium(II) complexes and the study of their redox properties.
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Angew Chem Int Ed Engl
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Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland.
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