In prospective study we investigated 92 patients after curettage. All women were treated with Doxycyclin immediately after curettage 2 times with 1 tablet of 100 mg every 12 hours for 3 days. With 72 of these patients we had feed-back and they were followed for signs of infection. In 49 patients (II group) emergency curettage was performed and in 23 patients (I group) a planning endometrial biopsy (Strich abrasio) was done. We noted 100% success rate in I group and 91.7% in II group with Doxycyclin for 3 days. Only in 6 patients (8.3%) of II group the continuing treatment with Doxycyclin was necessary for 6 days because of signs of infection. The use of Doxycyclin after curettage for 3 days decreases the risk of infection and only the doctor will decide the usage of antibiotic for 6 days.
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Niger Med J
January 2025
Department of Medical Laboratory Services, Federal Medical Center, Yenagoa, Bayelsa State, Nigeria.
Cholera remains a significant public health challenge in Nigeria, with recurrent outbreaks exacerbated by inadequate water, sanitation, and hygiene (WASH) infrastructure, as well as conflict and displacement. This review examines cholera outbreaks in Nigeria from 2010 to 2024, analyzing epidemiological trends, contributing factors, and public health responses. Seasonal peaks during periods of heavy rainfall and flooding have consistently facilitated transmission, with Northern regions disproportionately affected due to poor infrastructure and ongoing conflicts.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
January 2025
Orthodontic Department, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Objective: The orthodontic mini-implant (OMI) failure often occurs due to the accumulation of peri-implantitis bacteria surrounding it, which results in a stable, resistant form of absolute skeletal anchorage during orthodontic treatment. Administering doxycycline may be the solution, but long-term side effects result in antibiotic resistance. Roselle flowers (Hibiscus sabdariffa) possess beneficial active phytochemical substances, which may have potential as an OMI peri-implantitis alternative therapy.
View Article and Find Full Text PDFTrop Biomed
December 2024
Resource Biotechnology Programme, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300, Kota Samarahan, Sarawak, Malaysia.
Leptospirosis is a severe and potentially fatal re-emerging zoonotic and waterborne disease caused by pathogenic and intermediate species of Leptospira. Given the high global rates of morbidity and mortality associated with this disease, there is an urgent need to explore alternative therapeutic agents to enhance treatment options. This study investigates the anti-leptospiral efficacy of several common antibiotics-penicillin G, doxycycline, ampicillin, amoxicillin, cefotaxime, chloramphenicol, and erythromycin, as well as extracts from local herbs, Hydnophytum formicarum Jack and Boesenbergia stenophylla, against pathogenic and intermediate Leptospira strains.
View Article and Find Full Text PDFTrop Biomed
December 2024
Department of Critical Care Medicine, The Fourth Affiliated Hospital, School of Medicine, Zhejiang University, No. N1 Shangcheng Avenue, Yiwu, Zhejiang 322000, China.
Scrub typhus is an infectious disease caused by Orientia tsutsugamushi. It is transmitted through bite of chigger mite larvae and presents with symptoms such as fever, myalgia, headache, rash, and a characteristic eschar at the site of mite bites. This report details the case of a woman exhibiting acute febrile illness, bilateral pneumonia, and severe hypoxemia, prompting suspicion of scrub typhus due to the presence of a typical eschar on the pubic mound.
View Article and Find Full Text PDFJ Dermatolog Treat
December 2025
Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Purpose: Dupilumab is a widely recommended treatment for moderate-to-severe atopic dermatitis (AD), with known ocular side effects but less frequent cutaneous reactions.
Material And Methods: This case report details a 52-year-old female patient with atopic dermatitis treated with dupilumab. After an initially successful treatment, the patient developed a rosacea-like dermatitis.
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