10Sa RNA, a small stable RNA of Escherichia coli, is functional.

Mol Gen Genet

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.

Published: September 1991

The ssrA gene, coding for the metabolically stable 10Sa RNA, affects cell growth. A mutant in which the chromosomal 10Sa RNA gene is interrupted by a cat insert does not produce detectable levels of 10Sa RNA, and it grows more slowly than the parental strain.

Download full-text PDF

Source
http://dx.doi.org/10.1007/BF00264212DOI Listing

Publication Analysis

Top Keywords

10sa rna
16
10sa
4
rna small
4
small stable
4
rna
4
stable rna
4
rna escherichia
4
escherichia coli
4
coli functional
4
functional ssra
4

Similar Publications

Cooperative and Independent Functionality of tmRNA and SmpB in : A Multifunctional Exploration Beyond Ribosome Rescue.

Int J Mol Sci

January 2025

Pathogenesis and Control of Pathogenic Microorganisms Research Team, School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou 570228, China.

The trans-translation system, mediated by transfer-messenger RNA (tmRNA, encoded by the gene) and its partner protein SmpB, helps to release ribosomes stalled on defective mRNA and targets incomplete protein products for hydrolysis. Knocking out the and genes in various pathogens leads to different phenotypic changes, indicating that they have both cooperative and independent functionalities. This study aimed to clarify the functional relationships between tmRNA and SmpB in a pathogen that poses threats in aquaculture and human health.

View Article and Find Full Text PDF

We present a novel pathogenic and multidrug-resistant isolated from . The bacterium belongs to the Micrococcales order and has a genome consisting of 2.59 Mb in length and 71.

View Article and Find Full Text PDF

Plasmids are extrachromosomal genetic molecules that replicate independent of chromosomes in bacteria, archaea, and eukaryotic organisms. They contain diverse functional elements and are capable of horizontal gene transfer among hosts. While existing plasmid databases have archived plasmid sequences isolated from individual microorganisms or natural environments, there is a need for a comprehensive, standardized, and annotated plasmid database to address the vast accumulation of plasmid sequences.

View Article and Find Full Text PDF
Article Synopsis
  • - KACC92338, a strain isolated from Korean raw milk, exhibits strong antioxidant activities and can withstand high levels of hydrogen peroxide, showing significant protective effects on yeast cells against oxidative stress.
  • - The genomic analysis revealed KACC92338's composition of over 3,000 genes, with many related to probiotic properties, such as stress tolerance and adhesion to intestinal cells, while lacking any harmful antibiotic resistance or virulence factors.
  • - KACC92338 also possesses antimicrobial capabilities, evidenced by its clusters for bacteriocins and defense mechanisms like prophage regions and CRISPR systems, suggesting potential safe applications in food or health.
View Article and Find Full Text PDF

A draft genome sequence of an isolate of BSB from Santiniketan soil is being published. A. koreensis BSB produces lignocellulases, which are crucial in plant biomass degradation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!