AI Article Synopsis

  • A 72-year-old diabetic man experienced a benign papular eruption on his leg that progressed to necrotizing fasciitis despite treatment with antibiotics and surgery.
  • The severe infection ultimately required amputation to manage the spread of infection.
  • The infection was caused by Staphylococcus aureus with specific enterotoxin genes, yet it did not carry common toxin genes typically associated with severe infections.

Article Abstract

Benign papular eruption on the left leg of a 72-year-old diabetic man developed into rapidly spreading necrotizing fasciitis despite antimicrobial therapy and surgical debridements. This led to eventual amputation to control the infection. The etiological agent was a Staphylococcus aureus isolate harboring the enterotoxin gene cluster seg, sei, sem, sen, and seo but lacked all common toxin genes, including Panton-Valentine leukocidin.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829043PMC
http://dx.doi.org/10.1128/JCM.01657-06DOI Listing

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