AI Article Synopsis
- The study analyzed testicular and renal tissue from various animals and humans, focusing on the nuclear chromatin patterns of testicular primary spermatocytes and renal glomerular endothelial cells.
- The goal was to create a benchmark for identifying rapidly multiplying cells in healthy and abnormal mammalian tissues through digital image analysis.
- Results showed that the nuclear chromatin morphology and mitotic figures of renal glomerular endothelial cells are similar to those of testicular primary spermatocytes, suggesting both are involved in active cellular proliferation.
Article Abstract
Testicular and renal tissue, obtained from adult cattle, pigs, rats, and human was processed by image digital segmentation and pixel texture analytical techniques for comparative evaluation of nuclear chromatin pattern of testicular primary spermatocytes and renal glomerular endothelial cells. The post mortem performed for the animals and the human subject were for reasons not related with either testicular or renal conditions. The objective was to establish a benchmark for identification of rapidly multiplying cells in images of sections of normal, as well as abnormal mammalian tissue. Based on the observed morphological and texture pattern of the nuclear chromatin of the testicular primary spermatocytes, it was determined that the renal glomerular endothelial cells exhibit similar nuclear chromatin morphology consistent with an ongoing rapid multiplication process. The nuclear chromatin of both cell types manifest identical mitotic figures which are strongly indicative of cellular proliferation.
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| http://dx.doi.org/10.1016/j.compmedimag.2006.10.005 | DOI Listing |
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