[Structure: see text] An advanced intermediate in our planned synthesis of mitomycin C has been acquired in nine steps from tert-butyl glyoxylate. The aziridinyl pyrrolidine and quinone subunits are coupled regioselectively to arrive at an enamine that is prepared for C10 homologation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533355 | PMC |
| http://dx.doi.org/10.1021/ol0624676 | DOI Listing |
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