Objective: Determine the content of ursolic acid of Liuwei Dihuangwan.

Method: Using NIR with PLS, PCA-BPANN and WT-BPANN.

Result: The predication recovery were 100.7%, 100.6%, 100.1%, and the RSD were 5.42%, 6.49%, 6.52% respectively.

Conclusion: NIR can be used in the determination of ursolic acid, which set up the foundation of on-line control of traditional Chinese medicine.

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