Background: The NeoGuide Endoscopy System (NES) utilizes a fully articulated, computer-controlled insertion tube that allows proximal segments of the colonoscope to follow the path taken by the tip as it is manually advanced through the colon. The system was designed to eliminate looping and scope displacement during colonoscopy.
Material And Methods: Using in vitro testing, an inanimate flexible model of the colon incorporating four force transducers located at the key flexure points was employed to measure the axial forces on the colon wall during colonoscopy. In the second part of the study, 10 gastroenterologists performed colonoscopies, using a training latex-based simulator, with the NES and with a standard colonoscope. Colonic displacement was independently assessed by six gastroenterologists, with each evaluating endoscopist assigning a score between 0 and 5 corresponding to the maximum colonic displacement observed at any location.
Results: The average measured forces (in lbs) at three of the four flexure points were significantly lower ( P < 0.05) when the NES was used. The mean colonic displacement was significantly lower for procedures performed with the NES compared with the standard colonoscope (2.36 vs. 4.26, P < 0.001). Interobserver agreement regarding the degree of colonic displacement due to looping was moderate (weighted kappa = 0.45, P < 0.01).
Conclusions: Colonoscopy with the NES was associated with significantly less looping and lateral force required for advancement than procedures with a standard colonoscope. The reduced amount of looping suggests that use of the NES in patients might be associated with less discomfort and thus require less sedation.
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http://dx.doi.org/10.1055/s-2006-945014 | DOI Listing |
J Pediatr Gastroenterol Nutr
December 2024
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA.
Objectives: Colonic manometry catheter placement can be performed by colonoscopy or fluoroscopy. Our objective was to compare outcomes of colonoscopic to fluoroscopic catheter placement in children based on the extent of colon study and the likelihood of catheter displacement.
Methods: Colonic manometry studies performed between May 2015 and May 2022 were reviewed.
Dent J (Basel)
October 2024
Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Introduction: Gingival recession, characterized by the apical displacement of the gingival margin, presents challenges to oral health. This study compares the effectiveness of the coronally advanced flap (CAF) and the tunnel technique (TT) for treating gingival recessions.
Methods: Bibliographical searches included PubMed, Embase, Web of Science, Cochrane, Scopus, and the grey literature, with keywords "root coverage" "coronary advanced flap", and "tunnel".
Langmuir
November 2024
Grupo de Medios Porosos - Facultad de Ingeniería, Universidad de Buenos Aires, Av. Paseo Colón 850, C1063ACV Ciudad Autónoma de Buenos Aires, Argentina.
The objective of this work is the study of gas microbubble dissolution in a carrier liquid. To achieve this, we will analyze, using microfluidic techniques, the formation and evolution of carbon dioxide (CO) gas microbubbles in silicone oil, monitoring the size, position, and distance between the formed bubbles as they advance through a microchannel. This work consists of two parts (Part I and Part II): in Part I, we analyze the mechanisms determining the variation in the spatial frequency of bubbles as they move through the microchannel, while Part II examines the evolution of their size and demonstrates the utility of the device for obtaining diffusion coefficients and Henry's constant for the gases used.
View Article and Find Full Text PDFProbiotics Antimicrob Proteins
November 2024
Department of Agriculture, Food and Environment (Di3A), University of Catania, Santa Sofia Street, 100, 95123, Catania, Italy.
In the present study, twenty-seven (27) lactobacilli strains, isolated from the vagina of healthy Italian women of reproductive age, were screened for probiotic properties. The strains were evaluated for antagonistic activity against pathogens, adhesion abilities, and potential to displace and/or inhibit the adhesion of previously adhered pathogens as a primary strain selection criterion. Overall, all the tested lactobacilli inhibited at least three pathogens, and the majority of them exhibited antimicrobial activity against Enterobacter cloacae DSM 30054, Pseudomonas aeruginosa DSM 3227, and Pseudomonas aeruginosa DSM 1117.
View Article and Find Full Text PDFJ Glob Health
November 2024
Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Background: The full-scale invasion disrupted health care in Ukraine, leading to the displacement of physicians and affecting their access to subspecialist consultations. HealUA, a mobile application, was designed to provide secure and timely remote physician-to-physician consultations. We aimed to assess the implementation of the HealUA mobile application for peer-to-peer physician consultations in Ukraine during the Russian invasion.
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