The antifungal activity of methanolic extract and alkaloidal fraction of Berberis aetnensis against Candida species was investigated. The crude extract was active against Candida species, this activity being higher than that of the alkaloidal fraction and berberine.
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http://dx.doi.org/10.1016/j.fitote.2006.10.007 | DOI Listing |
ScientificWorldJournal
May 2015
Department of Biomedical Sciences, Microbiology Section, University of Catania, Via Androne 81, 95125 Catania, Italy.
Berberis aetnensis C. Presl (Berberidaceae) is a bushy-spiny shrub common on Mount Etna (Sicily). We demonstrated that the alkaloid extract of roots of B.
View Article and Find Full Text PDFJ Pharm Pharmacol
December 2013
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Italy.
Objectives: This study involves for the first time the evaluation of Berberis aetnensis C. Presl. and Berberis libanotica Ehrenb.
View Article and Find Full Text PDFPhytother Res
June 2011
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy.
Berberis aetnensis C. Presl. is a bushy-spiny shrub common on Mount Etna (Sicily, Italy), containing various alkaloids with several pharmacological properties.
View Article and Find Full Text PDFFitoterapia
February 2007
Department of Microbiological and Gynecological Sciences, Microbiology Section, University of Catania, Catania, Italy.
The antifungal activity of methanolic extract and alkaloidal fraction of Berberis aetnensis against Candida species was investigated. The crude extract was active against Candida species, this activity being higher than that of the alkaloidal fraction and berberine.
View Article and Find Full Text PDFInt J Antimicrob Agents
July 2003
Department of Microbiological and Gynaecological Sciences, Section of Microbiology, University of Catania,Via Androne 81, 95124 Catania, Italy.
Previous research showed that berberine-containing Berberis species synthesise the substances 5'-methoxyhydnocarpin-D (5'-MHC-D) and pheophorbide a, which have no antimicrobial activity but inhibit the expression of multidrug resistant efflux pumps (MDRs) in Staphylococcus aureus and potentiate the action of berberine. The MDR pumps extrude synthetic and natural antimicrobials from bacterial cells. We searched for these compounds in Berberis aetnensis C.
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