Objective: The present study intended to investigate whether there was a relationship between pregnant women with dyspeptic complaints and with and without Helicobacter pylori infection in the first and second trimester of pregnancy.
Methods: H.pylori seropositivity was determined in 146 (aged 20 to 40 years) antenatal patients at 10 to 23 weeks gestation. H.Pylori ser um Immunoglobulin IgG antibody concentrations were determined by enzyme-linked immunoadsorbent assay (ELISA). Age, obesity, parity, outcome of pregnancy and dyspeptic symptoms were registered in the patients' medical records. Chi-square and Student's t-test were used for statistical analysis of the data.
Results: Prevalence of H.pylori infection in the population studied was 65.7% (96 of 146). H pylori infection was not associated with parity, preterm delivery, obesity or with dyspeptic symptoms. Women positive for H.pylori IgG were older (30, 45 +/- 6.87 vs 27, 96 +/- 7.44, p= 0.045565*) than H. pylori negative patients.
Conclusion: In this study there was no association of H pylori infection with dyspeptic symptoms in pregnancy, nor was its presence associated with obesity, parity and outcome of pregnancy.
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