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High-Yield Preparation and Characterization of Feline Albumin with Antioxidant Properties and In Vivo Safety.

Int J Mol Sci

December 2024

Gene Engineering Laboratory, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

To address the limited supply of serum albumin (SA) and potential pathogen contamination, focus has been concentrated on the heterologous expression of human serum albumin (HSA), particularly in . However, there are rare studies on feline serum albumin (FSA), which requires a large amount in pet foods and clinical treatment. In this work, the codon-optimized recombinant feline serum albumin (rFSA) sequence was designed and transferred into GS115 for recombinant expression.

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Artificial Intelligence-based Assessment of Facial Symmetry Aesthetics of Saudi Arabian Population.

Facial Plast Surg

November 2024

Department of Orthodontic and Pediatric Dentistry, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.

The purpose of this study is to investigate facial symmetry aesthetics (FSA) in the Saudi Arabian population using artificial intelligence (AI).Two hundred and ten people from a range of demographic backgrounds participated in an observational cross-sectional study that was done at a hospital. Standardized posed photos of the face and smile were taken using a Canon camera utilizing a stratified random sample approach.

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Various studies have reported the use of alkali-activated composites to enable sustainable development in the construction industry as these composites eliminate the need for cement. However, few studies have used ferronickel slag aggregates (FSAs) as an aggregate material for alkali-activated composites. Alkali-activated composites are environmentally friendly and sustainable construction materials that can reduce carbon dioxide emissions from cement production, which accounts for 7% of global carbon emissions.

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Shiga-toxin producing (STEC) O157 is a food-borne pathogen which causes gastrointestinal illness in humans. Ruminants are considered the main reservoir of infection, and STEC exceedance has been associated with heavy rainfall. In September 2022, a large outbreak of STEC O157:H7 was identified in the United Kingdom (UK).

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Impact of the Novel MRI Contrast Agent Gadopiclenol on Radiotherapy Decision Making in Patients With Brain Metastases.

Invest Radiol

February 2025

From the Department of Radiation Oncology, University Hospital Bonn, University of Bonn, Bonn, Germany (G.R.S., L.C.S., D.K., A.F.); Department of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany (J.F., M. Eckl, F.S., A.R., F.A.G.); Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany (M.B.); Department of Radiology, University of Manitoba, Winnipeg, Manitoba, Canada (M. Essig); and University Medical Center Freiburg, Freiburg University, Freiburg, Germany (F.W.).

Article Synopsis
  • The study aimed to compare the effectiveness of two MRI contrast agents, gadopiclenol and gadobenate dimeglumine, in influencing treatment decisions between whole-brain radiotherapy (WBRT) and stereotactic radiosurgery (SRS) for patients with brain metastases.
  • In a double-blind crossover study, 13 patients underwent two MRI scans with both contrast agents, allowing radiation oncologists to outline tumor volumes and decide on treatment plans based on the imaging results.
  • The findings showed that gadopiclenol identified more brain metastases than gadobenate dimeglumine in over half of the patients, and treatment plans were altered for 15% of the patients based on the differences in imaging outcomes.
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