Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693609 | PMC |
| http://dx.doi.org/10.1136/bmj.39051.725162.3A | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Shark chondroitin sulfate gold nanoparticles: A biocompatible apoptotic agent for osteosarcoma.
Int J Biol Macromol
December 2024
College of Material Science and Engineering, Huaqiao University, Engineering Research Center of Environment-Friendly Functional Materials, Ministry of Education, Xiamen 361021, PR China. Electronic address:
Osteosarcoma is a highly aggressive tumor that originates in the bone and often infiltrates nearby bone cells. It is the most prevalent type of primary bone cancer among the various bone malignancies. Traditional cancer treatment methods such as surgery, chemotherapy, immunotherapy, and radiotherapy have had restricted success.
View Article and Find Full Text PDFGrowth of a Tessellation: Geometric rules for the Development of Stingray Skeletal Patterns.
Adv Sci (Weinh)
December 2024
Max Planck Institute of Colloids and Interfaces, Potsdam Science Park, Am Mühlenberg 1 OT Golm, 14476, Potsdam, Germany.
The skeletons of sharks and rays, fashioned from cartilage, and armored by a veneer of mineralized tiles (tesserae) present a mathematical challenge: How can the continuous covering be maintained as the skeleton expands? This study, using microCT and custom visual data analyses of growing stingray skeletons, systematically examines tessellation patterns and morphologies of the many thousand interacting tesserae covering the hyomandibula (a skeletal element critical to feeding), over a two-fold developmental change in hyomandibula length. The number of tesserae remains surprisingly constant, even as the hyomandibula expands isometrically, with all hyomandibulae displaying self-similar distributions of tesserae shapes/sizes. Although the distribution of tesserae geometries largely agrees with the rules for polyhedra tiling of complex surfaces-dominated by hexagons and a minor fraction of pentagons and heptagons, but very few other polygons-the agreement with Euler's classic mathematical laws is not perfect.
View Article and Find Full Text PDFRevealing chemistry-structure-function relationships in shark vertebrae across length scales.
Acta Biomater
November 2024
Department of Chemistry and Biochemistry, Department of Ocean and Mechanical Engineering, Florida Atlantic University, Boca Raton, FL 33431, USA. Electronic address:
Shark cartilage presents a complex material composed of collagen, proteoglycans, and bioapatite. In the present study, we explored the link between microstructure, chemical composition, and biomechanical function of shark vertebral cartilage using Polarized Light Microscopy (PLM), Atomic Force Microscopy (AFM), Confocal Raman Microspectroscopy, and Nanoindentation. Our investigation focused on vertebrae from Blacktip and Shortfin Mako sharks.
View Article and Find Full Text PDFOptimization of Automated Dimethylmethylene Blue Assay for Quantification of Pediatric Urine Samples.
Indian J Clin Biochem
October 2024
Department of Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
The metachromatic dye dimethylmethylene blue is used to quantify total glycosaminoglycans in urine. Understanding the interaction of dimethylmethylene blue with glycosaminoglycans is pertinent to optimize the assay procedure depending on the type of sample and interpret the findings meaningfully. The present spectrophotometric study determined the optimum sample-to-dye ratio, primary wavelength for measuring absorbance, after studying the interaction of two different chondroitin sulfate species (unfractionated chondroitin sulfate from bovine trachea vs.
View Article and Find Full Text PDFShark Cartilage-Derived Anti-Angiogenic Peptide Inhibits Corneal Neovascularization.
Bioengineering (Basel)
July 2024
College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Corneal neovascularization is a significant cause of vision loss, often resulting in corneal clouding and chronic inflammation. Shark cartilage is widely recognized as a significant natural source of anti-angiogenic compounds. Our previous studies have shown that a polypeptide from white-spotted catshark ( Bonnet) has the potential to inhibit the angiogenesis of breast tumors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!