Ring-cleaved pleuromutilin derivatives comprised of a [5.3.1] bicyclic core structure have been synthesized and evaluated in vitro as antibacterial agents. Four of the compounds described were found to have MICs
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http://dx.doi.org/10.1016/j.ejmech.2006.07.018 DOI Listing Publication Analysis
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Cyclopentanone ring-cleaved pleuromutilin derivatives.
Eur J Med Chem
January 2007
Anti-infective Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, P.O. Box 5100, Wallingford, CT 06492, USA.
Ring-cleaved pleuromutilin derivatives comprised of a [5.3.1] bicyclic core structure have been synthesized and evaluated in vitro as antibacterial agents.
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