Rituximab induced hypoglycemia in non-Hodgkin's lymphoma.

World J Surg Oncol

Division of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.

Published: December 2006

Background: Hypoglycemia is a vary rare toxicity of rituximab. The exact mechanism of rituximab induced hypoglycemia is not clear.

Case Presentation: A 50 year old female presented with a left tonsillar non Hodgkin's lymphoma and was started on R-CHOP chemotherapy. Twenty four hours after the first rituximab infusion, she developed hypoglycemia which was managed by IV glucose infusion.

Conclusion: Hypoglycemia following rituximab administration is rare. Possibilities of hypoglycemia should be kept in mind in patients developing symptoms like fatigue, restlessness, and sweating while on rituximab therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764014PMC
http://dx.doi.org/10.1186/1477-7819-4-89DOI Listing

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