Photoinduced repair of a thymine dimer in DNA via carbazole nucleoside.

Nucleic Acids Symp Ser (Oxf)

School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan.

Published: August 2007

We report the photoinduced repair of a thymine dimer incorporated in a DNA duplex via oligodeoxynucleotide (ODN) containing carbazole nucleoside (K). The occurrence of an electron transfer between K and thymine dimer is evidenced by fluorescence quenching measurements. K acts as a good electron donor for the photoinduced repair of a thymine dimer.

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http://dx.doi.org/10.1093/nass/nrl075DOI Listing

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