Structural stability and length of I-motif of G-quartet in DNA octaplex.

Nucleic Acids Symp Ser (Oxf)

Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama 226-8501, Japan.

Published: July 2007

To confirm that longer DNA strands with sequences gcGA[G](n)Agc can form an octaplex, X-ray analyses at n>1 have been performed. Several crystals of d(gcGA[G]2Agc) are obtained under different conditions. It has been found that the crystal obtained with cobalt hexamine suggests a hexaplex formation, while the crystal obtained with Mg2+ and Na+ ions suggests an octaplex formation.

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Source
http://dx.doi.org/10.1093/nass/48.1.121DOI Listing

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