This paper describes DNA analog synthesis consisting of the benzene-phosphate backbone, of which the monomer units are built from benzene-core units connected via a biaryl-like axis to the nucleobases. It was found that the duplex comprised of the analogs had a non-helical structure and was thermally more stable than the corresponding natural DNA duplex.
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http://dx.doi.org/10.1093/nass/48.1.17 | DOI Listing |
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