Objective: This study investigated differences regarding degree, duration, and motivation of abstinence within a group of individuals with very low alcohol consumption. Reliability of self-reported alcohol abstinence was examined.
Method: Interview data on alcohol intake and abstinence were investigated in 412 male and 377 female population-representative participants of the cross-sectional KORA/ MAGiC-Control study. This study was conducted in 2002 in the region of Augsburg, Germany, with participants who were 28-77 years old.
Results: The group of persons with very low alcohol consumption (0 to =3 g per day; n = 312) comprised 73 nonlifetime abstainers and 40 lifetime abstainers. Duration of abstinence in nonlifetime abstainers ranged from less than 1 year to 50 years (median = 13 years). The median proportion of their adult life, during which nonlifetime abstainers had been abstinent, was 35% for individuals who were 58 years or older and 37% for younger individuals. Motivation for abstinence differed between lifetime abstainers and nonlifetime abstainers (p < .0001). Lifetime abstainers were more likely than nonlifetime abstainers to cite negative or indifferent feelings toward use of alcohol (76% vs 30%; p < .0001), whereas nonlifetime abstainers mentioned medical (42% vs 16%; p = .004) and other reasons (28% vs 8%; p = .009) more often than did lifetime abstainers. Using data from a prior survey, 91% of teetotalers reliably answered the question on alcohol abstinence.
Conclusions: Direct questioning about alcohol abstinence was acceptable and participants' answers were reliable. Heterogeneity within teetotalers was confirmed for starting age of abstinence and motivation. Future epidemiological studies should put more emphasis on exact categorization of alcohol consumption and abstinence.
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http://dx.doi.org/10.15288/jsad.2007.68.6 | DOI Listing |
AIDS Behav
January 2025
Rollins School of Public Health, Emory University, 1518 Clifton Rd. NE Atlanta GA, Atlanta, 30322, USA.
This study aimed to explore the awareness, willingness, and engagement with pre-exposure prophylaxis (PrEP) among high-risk Chinese men who have sex with men (MSM) and to investigate the factors influencing its use. A cross-sectional survey of 1800 HIV-negative MSM was conducted in Chengdu, Suzhou, and Wuhan between June 2022 and February 2023 through in-person and online recruitment methods. Univariate and multivariate logistic regression analyses were used to identify predictors of PrEP use.
View Article and Find Full Text PDFLab Chip
January 2025
CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, P. R. China.
We propose a novel contactless droplet manipulation strategy that combines electrostatic tweezers (ESTs) with lubricated slippery surfaces. Electrostatic induction causes the droplet to experience an electrostatic force, allowing it to move with the horizontal shift of the EST. Because both the EST and the slippery operating platform prepared by a femtosecond laser exhibit a strong binding effect on droplets, the EST droplet manipulation features significant flexibility, high precision, and can work under various operating conditions.
View Article and Find Full Text PDFFront Public Health
January 2025
College of Physical Education and Health, Guangxi Normal University, Guilin, China.
Objective: This study aims to assess the relationship between modifiable dementia risk factors and both dementia and cognitive decline.
Methods: Data were obtained from the Health and Retirement Study (HRS) [2008-2020], the China Health and Retirement Longitudinal Study (CHARLS) [2011-2020], and the English Longitudinal Study of Ageing (ELSA) [2010-2020]. After adjusting for confounding factors, multivariable logistic regression was utilized to analyze the relationship between modifiable dementia risk factors and dementia, while multivariable linear regression was employed to examine the relationship between these risk factors and cognitive decline.
Risk Manag Healthc Policy
January 2025
Université Paris Cité, Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Team Vulnerability of Psychiatric and Addictive Disorders, Paris, France.
Purpose: Alcohol use is a leading risk factor for preventable death, injury, and disease globally. Low sensitivity to the effects of alcohol is influenced by genes and predicts risk for harmful alcohol use and alcohol use disorder (AUD). Alcohol induces effects partly by modulation of gamma-aminobutyric acid receptors type A (GABARs).
View Article and Find Full Text PDFBMC Med
January 2025
Department of Cardiology, The Third Xiangya Hospital of Central South University, Yuelu District, 138 Tongzipo Road, Changsha, 410013, Hunan, China.
Background: Guidelines recognized dual combination in initial antihypertensive therapy. Studies found that low-dose quadruple combination were superior to monotherapy. However, whether low-dose quadruple therapy is better than dual combination is unknown.
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