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Improvement of Mucoid Impaction with Dupilumab in a Severe Asthma Patient.
Maedica (Bucur)
June 2024
Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Japan.
Different from intrabronchial mucus accumulation in bronchiectasis caused by chronic inflammation, mucoid impactions are observed in patients with allergic bronchopulmonary aspergillosis (ABPA) and bronchial asthma. A 62-year-old man was referred to our hospital for treatment of bronchial asthma. Five years ago, he had a coronary stent insertion for myocardial infarction and was diagnosed with bronchial asthma.
View Article and Find Full Text PDFCT Imaging Assessment of Response to Treatment in Allergic Bronchopulmonary Aspergillosis in Adults With Bronchial Asthma.
Chest
June 2024
Service de Pneumologie et Oncologie Thoracique, Centre constitutif Maladies pulmonaires rares, Université Paris Sorbonne, Assistance Publique - Hôpitaux de Paris, Hôpital Tenon, Paris, France.
Background: One of the major challenges in managing allergic bronchopulmonary aspergillosis remains consistent and reproducible assessment of response to treatment.
Research Question: What are the most relevant changes in CT scan parameters over time for assessing response to treatment?
Study Design And Methods: In this ancillary study of a randomized clinical trial (NebuLamB), patients with asthma with available CT scan and without exacerbation during a 4-month allergic bronchopulmonary aspergillosis exacerbation treatment period (corticosteroids and itraconazole) were included. Changed CT scan parameters were assessed by systematic analyses of CT scan findings at initiation and end of treatment.
Lobar Mucus Plugging Reflecting Central Bronchial Tumoral Obstruction: A Case Report.
Cureus
November 2023
Radiology, Centre Hospitalier EpiCURA - site de Ath, Ath, BEL.
Early diagnosis of bronchopulmonary carcinoid tumors is crucial as the surgical excision is the main treatment and determines the prognosis. We present the case of a 66-year-old heavy-smoker man who had started to complain about a cough a few months ago. We diagnosed him with an endobronchial mass on a chest computed tomography scan and lobar bronchoceles resulting from mucus plugging distal to the tumor obstruction.
View Article and Find Full Text PDFOverlap of Chronic Pulmonary Aspergillosis on Allergic Bronchopulmonary Aspergillosis.
Intern Med
August 2024
Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.
An 80-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) was admitted to our institution in 2023 for an enlarged pulmonary mass lesion. She had developed ABPA in 2017, and corticosteroid therapy had improved the mucoid impaction of the bronchi. Because part of the lesion remained, increased doses of corticosteroid, antifungals, and biologics were administered, but the pulmonary lesion enlarged in 2022.
View Article and Find Full Text PDFAllergic bronchopulmonary aspergillosis manifested secondary to bacterial pleural empyema.
Respirol Case Rep
January 2024
Department of Respiratory Medicine, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
A 54-year-old woman with no history of lung disease including bronchial asthma developed left bacterial pleural empyema due to the perforation of a lung abscess in the left lower lobe. Chest tube drainage and antibiotics improved the pleural empyema. Two months following discharge from the hospital, she developed a cough and left chest pain.
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