AI Article Synopsis
- The study investigated how hope, illness-related uncertainty, anxiety, depression, and treatment adherence are connected in children who have undergone renal and liver transplants.
- Seventy children and their caregivers completed questionnaires over three months while their adherence to treatment was tracked through self-reports and electronic monitoring.
- Results indicated that hope and uncertainty influence anxiety and depression, which in turn affects treatment adherence, highlighting the need for targeted interventions for improving adherence in pediatric transplant patients.
Article Abstract
Objective: To examine, using partial least squares (PLS) modeling, the associations among hope, illness-related uncertainty, anxiety, depression, and adherence in a sample of children with renal and liver transplantations.
Methods: Seventy pediatric renal and liver transplant recipients and their caregivers participated in a 3-month study which involved completing questionnaires and monitoring adherence via self-report and electronic monitoring (MEMS caps). A PLS estimation procedure was used to examine the associations among constructs in the theoretical model.
Results: Hope and uncertainty were associated with both depressive symptoms and anxiety, and depressive symptoms were associated with treatment adherence. The association of hope and adherence to treatment was fully mediated by depressive symptoms.
Conclusions: Findings suggest mechanisms for identifying patients that may be at risk for nonadherence and components for intervention programs to improve adherence rates among pediatric transplant recipients.
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| http://dx.doi.org/10.1093/jpepsy/jsl046 | DOI Listing |
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