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Eukaryotic cells have several quality control systems that monitor the proper processing of RNAs during RNA biogenesis or the function of cytoplasmic mRNAs. A recent study in Molecular Cell by LaRiviere et al. (2006) shows that after production, mature rRNA is also subject to quality control and nonfunctional ribosomes are targeted for destruction by a novel ribosome surveillance mechanism.
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| http://dx.doi.org/10.1016/j.devcel.2006.11.004 | DOI Listing |
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