[The extended lymphadenectomy in the treatment of gastric cancer].

Ann Ital Chir

Università degli Studi di Napoli Federico II, Dipartimento di Scienze Chirurgiche Ortopediche Traumatologiche ed Emergenze, Area Funzionale di Chirurgia Generale, Napoli.

Published: February 2007

Introduction: The only potentially curative modality of localized gastric cancer is surgery. However there is area of disagreement among surgeons with respect to the appropriate extent of lymphadenectomy.

Methods: The retrospective study of a personal experience on 155 patients with gastric cancer; the patients were divided in two groups with respect to the extent of lymphadenectomy.

Results: The results of this study highlight the more effectiveness of D2 resection compared with D1 resection with respect to 5th year survival.

Discussion: The goal of treatment is to reduce the risk of recurrent disease. There is considerable debate as to whether the routine use of an extensive en-bloc resection of second echelon lymph nodes (D-2 resection) is superior to a more limited lymphadenectomy of the perigastric lymph nodes (D-1 resection). Therefore the survival benefit of D2 dissection appears to be limited to N2 disease.

Conclusion: Since nodal status prediction before or during surgery is inaccurate, all patients with curable disease, including those with N0 or NI disease, should undergone extensive node dissection.

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