Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jaci.2006.06.011 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of oxygen concentration on time to resolution of spontaneous pneumothorax in term infants: a population based cohort study.
BMC Pediatr
August 2014
Department of Pediatrics, University of Calgary, Foothills Medical Centre, Rm C211, 1403-29TH Street, T2N 2 T9 Calgary, Alberta, Canada.
Background: Little evidence exists regarding the optimal concentration of oxygen to use in the treatment of term neonates with spontaneous pneumothorax (SP). The practice of using high oxygen concentrations to promote "nitrogen washout" still exists at many centers. The aim of this study was to identify the time to clinical resolution of SP in term neonates treated with high oxygen concentrations (HO: FiO2 ≥ 60%), moderate oxygen concentrations (MO: FiO2 < 60%) or room air (RA: FiO2 = 21%).
View Article and Find Full Text PDFReceptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo.
PLoS One
December 2010
Department of Physiology, Michigan State University, East Lansing, Michigan, United States of America.
Rationale: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Objectives: Extending this work to beta 2 adrenergic systems in vitro and in vivo.
Methods: Ultraviolet spectroscopy was used to study ascorbate binding to adrenergic receptor preparations and peptides.
Bradykinin inducible receptor is essential to lipopolysaccharide-induced acute lung injury in mice.
Eur J Pharmacol
May 2010
Laboratory of Transplantation Immunobiology, Department of Immunology, University of São Paulo, Av. Prof. Lineu Prestes, 1730, ICB IV, 05508-900, São Paulo, SP, Brazil.
Lipopolysaccharides from gram-negative bacteria are amongst the most common causative agents of acute lung injury, which is characterized by an inflammatory response, with cellular infiltration and the release of mediators/cytokines. There is evidence that bradykinin plays a role in lung inflammation in asthma but in other types of lung inflammation its role is less clear. In the present study we evaluated the role of the bradykinin B1 receptor in acute lung injury caused by lipopolysaccharide inhalation and the mechanisms behind bradykinin actions participating in the inflammatory response.
View Article and Find Full Text PDFInitial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles.
AAPS PharmSciTech
June 2009
School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Pharmaceutical aerosols have been targeted to the lungs for the treatment of asthma and pulmonary infectious diseases successfully. Micafungin (Astellas Pharma US, Deerfield, IL, USA) has been shown to be an effective antifungal agent when administrated intravenously. Pulmonary delivery of micafungin has not previously been reported.
View Article and Find Full Text PDFAcorns and inhalers: the Asthma Clinical Research Network.
J Allergy Clin Immunol
January 2007
Respiratory Disease Division, Brigham and Women's Hospital, Boston, MA, USA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!