Purpose: We designed an arm volumeter specifically for home use based on the water displacement method. The objective of this study was to determine its accuracy and precision, and compare it with a standard volumeter used in lymphedema clinics worldwide.
Patients And Methods: Using a standard model hospital volumeter and our own device, we took three consecutive measurements of 11 specially cast cylinders, which had known volumes ranging from 10 mL to 4 L, and measurements of both arms of 15 volunteers.
Results: Measurements with both volumeters were highly accurate (R2 = 0.9999) when compared with the known volumes of the cast cylinders, and were strongly correlated (R2 = 0.9974) when each arm volume was compared between volumeters. Measurements with our volumeter were more precise both with the cylinders (average standard deviation [SD], 3.2 v 8 mL; P = .0553) and with the arms (average SD, 11.1 v 19 mL; P = .0034). Whereas the standard volumeter is expensive, fragile (acrylic), and prone to leaks, our volumeter is inexpensive, virtually indestructible, leak proof, and suitable for home use.
Conclusion: Arm volumes can be measured quickly and accurately at home using a simple, inexpensive, and robust device based on water displacement. Readily accessible arm volumetry at home may have widespread influence on the management of lymphedema after breast cancer.
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http://dx.doi.org/10.1200/JCO.2006.07.9376 | DOI Listing |
Front Med (Lausanne)
February 2025
Department of Critical Care Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Background: Cipepofol is a highly selective gamma-aminobutyric acid A receptor potentiator. As a new sedative drug, detailed studies on its respiratory effects are further needed. The present study aims to investigate the effects of cipepofol on breathing patterns, respiratory drive, and inspiratory effort in mechanically ventilated patients.
View Article and Find Full Text PDFJ Robot Surg
March 2025
Institute of Academic Surgery (IAS), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Unlabelled: The study aims to analyze the outcomes of buccal mucosa and lingual mucosa graft reconstruction for repairing ureteral strictures, assessing the efficacy and safety of both surgical approaches.
Methods: A computer search was conducted on PubMed, Embase, and Web of Science using keywords such as "buccal mucosa", "lingual mucosa", "oral mucosa", "ureteral stenosis", and "ureteral reconstruction" to gather relevant literature on lingual mucosa and the efficacy of buccal mucosal reconstruction for ureteral repair. The search spanned from January 2000 to March 2024, focusing on experiments that assessed LMGU (lingual mucosa graft ureteroplasty) or BMGU (buccal mucosa graft ureteroplasty).
JMIR Res Protoc
March 2025
Department of Cardiology, Life Bay View Private Hospital, Mossel Bay, South Africa.
Background: Chronic heart failure has high morbidity and mortality, with approximately half of the patients dying within 5 years of diagnosis. Recent additions to the armamentarium of anti-heart failure therapies include angiotensin receptor-neprilysin inhibitors (ARNIs) and sodium/glucose cotransporter 2 inhibitors (SGLT2is). Both classes have demonstrated mortality and morbidity benefits.
View Article and Find Full Text PDFJ Asthma
March 2025
Medical Affairs, GSK, Mumbai, India.
ObjectiveExisting mepolizumab trials have excluded patients with severe asthma with an eosinophilic phenotype (SAEP) from India. This study (NCT04276233) investigated the safety and effectiveness of mepolizumab in Indian adults with SAEP.MethodsMulti-centre, open-label, single-arm, interventional study; patients received 100 mg mepolizumab subcutaneously every four weeks for 24 weeks.
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