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Improving ROP management: insights from a comparative analysis of screening and treatment modalities in a tertiary hospital, Pakistan.
BMC Ophthalmol
January 2025
Institute of Ophthalmolohy, King Edward Medical University, Lahore, Pakistan.
Background: The principal objective of our study is to evaluate the characteristics of babies with type 1 ROP, screening practices and treatment trends in a tertiary care centre in Pakistan.
Methods: This prospective study at Mayo Hospital, Lahore (July 2022-July 2024), included 89 preterm infants with type 1 ROP, selected using non-probability sampling. Infants were categorized based on international (GA < 32weeks or BW < 1500 g) and local screening criteria (GA < 35 weeks or BW < 2000 g), and treatment outcomes were evaluated across three groups: Anti-VEGF, combination therapy (Anti-VEGF followed by laser), and laser therapy.
Analysis of Factors Affecting Prolonged Air Leak and Expansion Failure in the Lung after Resection in Patients with Pulmonary Malignancy and Predictive Value of Preoperative Quantitative Chest Computed Tomography.
Thorac Cardiovasc Surg
January 2025
Department of Thoracic Surgery, Ege University Faculty of Medicine, Izmir, Türkiye.
Background: The factors affecting the prolonged air leak (PAL) and expansion failure in the lung in patients undergoing resection for lung malignancy were analyzed. In this context, the value of the percentage of low attenuation area (LAA%) measured on preoperative quantitative chest computed tomography (Q-: CT) in predicting the development of postoperative PAL and the expansion time of the remaining lung (ET) in patients undergoing resection for lung malignancy was investigated.
Methods: The data of 202 cases who underwent lung resection between July 2020 and December 2022 were analyzed.
Physical activity and content in a variety of physically active learning: an observational case study of real-world practices.
Front Sports Act Living
January 2025
Department of Sports, Physical Education and Outdoor Studies, Faculty of Humanities, Sports and Educational Science, University of South-Eastern Norway, Bø, Norway.
Background: Research on physically active learning (PAL) has mainly been investigated experimentally, where interventions have been introduced to study effects on, for example, physical activity (PA) levels. This might undermine real-world contexts and realistic PA levels when teachers have sustained PAL in their regular teaching practice for several years. The purpose of this study was to observe and describe the organization and content of a variety of teaching where PAL was enacted by experienced teachers and to describe the corresponding PA levels and PA intensity in real-world practices.
View Article and Find Full Text PDFInsights into eye genetics and recent advances in ocular gene therapy.
Mol Cell Probes
January 2025
Institute of Molecular and Clinical Ophthalmology Basel, Mittlere Strasse 91, Basel, CH-4031, Switzerland. Electronic address:
The rapid advancements in the field of genetics have significantly propelled the development of gene therapies, paving the way for innovative treatments of various hereditary disorders. This review focuses on the genetics of ophthalmologic conditions, highlighting the currently approved ophthalmic gene therapy and exploring emerging therapeutic strategies under development. Inherited retinal dystrophies represent a heterogeneous group of genetic disorders that manifest across a broad spectrum from infancy to late middle age.
View Article and Find Full Text PDFStudy of physical activity in obese adolescents in Algeria.
Arch Pediatr
January 2025
Laboratoire de Biomathématiques, Biophysique, Biochimie et Scientométrie (L3BS), Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000 Bejaia, Algérie; Centre de Recherche en Technologies Agro-alimentaires. Route de Targua Ouzemmour, 06000 Bejaia, Algérie.
Objective: Adolescents are meant to spend a large part of their time practicing a hobby or sport, but currently there is a decline in their level of physical activity and sport both inside and outside schools, which can lead to a risk of obesity. The objective of the present study was to examine physical activity in obese adolescents within the school establishments of the province of Bejaia (northeastern Algeria).
Method: To determine the physical activity level (PAL) in the school population, a sample of 3,038 students with obesity comprising 1,635 girls and 1,403 boys was selected.
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