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Cefiderocol AST in a real-life Klebsiella pneumoniae collection: challenges in the ATU range.
J Antimicrob Chemother
January 2025
Servicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Carretera de Colmenar Km 9,1. Madrid 28034, Spain.
Objectives: FDC susceptibility testing is challenging as none of the commercial tests have been proven to accurately determine the susceptibility in the area of technical uncertainty (ATU). Here, we evaluated the performance of different FDC testing methods on Klebsiella pneumoniae isolates around this range.
Methods: A challenging collection of 104 K.
Medical student perception of force application: An accuracy assessment and pilot training program.
J Educ Health Promot
November 2024
Department of Primary Care, Kansas City University College of Medicine, Department of Primary Care, Kansas City, MO, USA.
Background: It is unclear how accurately students can reproduce specific forces that are often required for physical examination maneuvers. This study aimed to determine the baseline accuracy of force application for preclinical medical students, evaluate the effectiveness of a quantitative visual feedback intervention, and investigate whether certain demographics influence accuracy.
Materials And Methods: First- and second-year medical students were enrolled and demographic data were collected.
Adenoid basal cell carcinoma: An underrecognized cervical malignancy.
Gynecol Oncol Rep
February 2025
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Long Island Jewish Medical Center, Zucker School of Medicine at Hofstra/Northwell, Northwell Health, New Hyde Park, NY 11040, United States.
Introduction: Adenoid basal cell carcinoma is a rare cervical malignancy which is indolent in nature but resembles more commonly occurring aggressive malignancies.
Cases: Here we describe three cases of cervical adenoid basal cell carcinoma. All patients had a history of cervical dysplasia with high-risk HPV.
Evaluation of predictions of disordered binding regions in the CAID2 experiment.
Comput Struct Biotechnol J
December 2024
Department of Computer Science, Virginia Commonwealth University, Richmond, VA 23284, USA.
A large portion of the Intrinsically Disordered Regions (IDRs) in protein sequences interact with proteins, nucleic acids, and other types of ligands. Correspondingly, dozens of sequence-based predictors of binding IDRs were developed. A recently completed second community-based Critical Assessments of protein Intrinsic Disorder prediction (CAID2) evaluated 32 predictors of binding IDRs.
View Article and Find Full Text PDFSoil contamination by heavy metals (HM) is a critical area of research. Traditional methods involving sample collection and lab analysis are effective but costly and time-consuming. This study explores whether geostatistical analysis with GIS and open data can provide a faster, more precise, and cost-effective alternative for HM contamination assessment without extensive sampling.
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