Objective: To examine information collected from the 2002 Health and Diet Survey regarding the use dietary supplements and self-reported health problems that the survey participants believed were related to dietary supplements.
Methods: The US Food and Drug Administration sponsors a Health and Diet Survey to track trends of consumer awareness, attitudes, and practices related to health and diet issues. By telephone, the 2002 Health and Diet Survey staff interviewed English-speaking noninstitutionalized adults aged 18 years or older in households in the 50 states and District of Columbia. Survey respondents were queried as to whether or not they had taken a dietary supplement during the past year and if they had experienced any health problem that they attributed to supplement use.
Results: Seventy-three percent of US noninstitutionalized adults aged 18 years or older who spoke English and resided in households with telephones used a dietary supplement in the previous 12 months and 4% of them had experienced an adverse event that they believed might be related to dietary supplement use. Eighty-five percent of supplement users reported taking multivitamins/multiminerals and 13.3% of adverse events reported were attributed to multivitamins/multiminerals. A higher proportion of supplement users with adverse events than users without adverse events were concurrently taking supplements and prescription drugs or were taking supplements instead of prescription drug to treat or prevent a health condition.
Conclusions: This self-reported data describes the prevalence of supplement use and related adverse events. Multivitamins/multiminerals accounted for much of the supplements use and was attributed to a little more than 10% of the adverse events reported. Food and nutrition-professionals and other health care professionals should take special care to learn about their patients' use of these products.
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http://dx.doi.org/10.1016/j.jada.2006.09.002 | DOI Listing |
Syst Rev
December 2024
West China Center of Excellence for Pancreatitis, Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.
Background: Sepsis is a life-threatening organ dysfunction with high morbidity and mortality. Various studies have demonstrated the effectiveness of Chinese tonic medicines (CTMs) in treating sepsis or septic shock. However, trials directly comparing the efficacy and safety of different CTMs for sepsis or septic shock are still lacking.
View Article and Find Full Text PDFBMC Surg
December 2024
Department of Geriatric Medicine, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, 9 Jiaowei Road, Wenzhou city, Zhejiang Province, 325000, China.
Background: Coronary artery bypass grafting (CABG) remains the preferred treatment for complex multi-vessel coronary artery disease, offering substantial long-term benefits. Non-cardiac comorbidities such as frailty may significantly affect the outcomes of this procedure. However, the exact impact of frailty on CABG outcomes remains unclear, particularly given its exclusion from many pivotal revascularization trials.
View Article and Find Full Text PDFAm J Cardiovasc Drugs
December 2024
Cardiology A Department, Research Laboratory LR12 SP 16 Fattouma Bourguiba University Hospital, University of Monastir, Monastir University, Rue du 1er juin 1955, 5000, Monastir, Tunisia.
Unlabelled: BACKGROUND AND OBJECTIVE: Left atrial strain (LAS) has prognostic value in patients with atrial fibrillation (AF). Consequently, therapies that improve LAS may help reduce AF-related adverse cardiac events. We aimed to compare how digoxin and bisoprolol modulate LAS in patients with AF being treated with rate control.
View Article and Find Full Text PDFInvest New Drugs
December 2024
Division of Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Antiangiogenic drugs may cause vascular normalization and correct hypoxia in tumors, shifting cells to mitochondrial respiration as the primary source of energy. In turn, the addition of an inhibitor of mitochondrial respiration to antiangiogenic therapy holds potential to induce synthetic lethality. This study evaluated the mitochondrial inhibitor ME-344 in combination with bevacizumab in patients with refractory metastatic colorectal cancer (mCRC).
View Article and Find Full Text PDFInfect Control Hosp Epidemiol
December 2024
Rush University Medical Center, ChicagoIL, USA.
Background: Diagnostic stewardship of urine cultures from patients with indwelling urinary catheters may improve diagnostic specificity and clinical relevance of the test, but risk of patient harm is uncertain.
Methods: We retrospectively evaluated the impact of a computerized clinical decision support tool to promote institutional appropriateness criteria (neutropenia, kidney transplant, recent urologic surgery, or radiologic evidence of urinary tract obstruction) for urine cultures from patients with an indwelling urinary catheter. The primary outcome was a change in catheter-associated urinary tract infection (CAUTI) rate from baseline (34 mo) to intervention period (30 mo, including a 2-mo wash-in period).
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