Background: Affective disorder, once seen as rare in sub-Saharan Africa, is now viewed as more common. There are however challenges in assessing rates of depression, exploring manifestations of depression, and understanding risk factors for depression, especially those related to gender.
Aim: To identify key themes and new directions for research on affective disorder in sub-Saharan Africa, with particular reference to gender issues.
Methods: Interpretive review of selected literature, and theoretical analysis.
Results: There are gender differences in manifestations and rates of depression in sub-Saharan Africa, and there are forms of presentation (largely somatic, based on interpersonal relationships, or spiritual in nature) which may obscure the detection of depression. Studies are consistent however that when depressive symptoms are sought and are present, these are reasonably easy to elicit.
Limitations: This was not a systematic review, and the substantial grey literature from sub-Saharan Africa was not reviewed. For many countries, there are no data available.
Conclusions: Affective disorder, when properly sought for through both qualitative and quantitative methods, has been found to be common in sub-Saharan Africa. There is a paucity of research on interventions with affective disorder in this region.
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http://dx.doi.org/10.1016/j.jad.2006.09.029 | DOI Listing |
Microbiology (Reading)
January 2025
Clinical Infection, Microbiology & Immunology Department, Institute of Infection, Veterinary & Ecological Sciences, University of Liverpool, Liverpool, UK.
Typhimurium is a major serovar that is found globally. It is responsible for outbreaks of self-limiting gastroenteritis that are broadly linked to the industrialization of food production. .
View Article and Find Full Text PDFAlzheimers Dement
December 2024
College of Medicine, University of Ibadan, Ibadan, Nigeria.
Background: Understanding the genetic underpinnings of Alzheimer's disease is crucial for advancing research and developing targeted interventions. Genomic research in dementia in Africa is of utmost importance based on recent reports from studies in African Americans that African ancestral gene is associated with lower risk effect for developing AD. However, dementia related genetic study is an evolving research in sub-Saharan Africa with peculiar challenges influencing participant recruitment.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Multi-Ethnic Health Equity Research Center, University of California, San Francisco, San Francisco, CA, USA.
Background: Prior studies suggest that neighborhood socioeconomic status, neighborhood walkability, and neighborhood social cohesion are associated with cognitive function and dementia risk. However, little is known about how neighborhood social and built environments influence dementia risk in South Asian populations residing in the US.
Methods: We used data from 745 South Asian individuals ≥40 years in the US who completed Exam 2 (2015-2018) of the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study.
Alzheimers Dement
December 2024
Global Brain Health Intitute, TCD, Dublin, Dublin, Ireland.
Background: A healing garden is a non-pharmacological approach that supports the interaction of humans and elements of nature towards improving well-being and quality of life. It has gained increased utilization in managing the health outcomes of older persons with and without dementia. However, there is a paucity of evidence of its use and benefits in African countries with increasing prevalence of dementia, such as Nigeria.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Female Brain Health and Endocrine Research (FemBER) Consortium, Newcastle, Edinburgh, London, United Kingdom.
Background: The Global Dementia Action Plan 2017-2025 specifies key targets, with an emphasis on building research infrastructure and capability across the Global South. However, to date, only 0.1% of total research in Africa constitutes dementia research, the lowest volume of all LMIC regions.
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