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Preablative Stimulated Thyroglobulin Levels Can Predict Malignant Potential and Therapeutic Responsiveness of Subcentimeter-Sized, 18F-fluorodeoxyglucose-Avid Cervical Lymph Nodes in Patients With Papillary Thyroid Cancer.
Clin Nucl Med
January 2016
From the *Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Jeonnam, Republic of Korea; †Department of Nuclear Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea, ‡Department of Radiology, Chonnam National University Hospital, Gwangju, Republic of Korea; §Department of Nuclear Medicine, Chosun University Hospital, Gwangju, Republic of Korea.
Purpose: We investigated the potential value of TSH-stimulated serum thyroglobulin (sTg) to characterize subcentimeter-sized, F-FDG avid cervical lymph nodes (LNs) on 18PET/CT and their responsiveness to 131I ablation therapy (IAT) in patients with papillary thyroid cancer.
Materials And Methods: We enrolled 49 patients who were undergoing total thyroidectomy and had incidentally detected FDG-avid LNs on PET/CT before IAT. According to the follow-up results, FDG-avid LNs were classified into 2 groups: those with metastatic LNs (group A) and those with benign LNs (group B).
18F-fluorodeoxyglucose-avid thyroid incidentalomas in patients with lymphoma.
Isr Med Assoc J
October 2006
Department of Surgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Resistance of [18f]-fluorodeoxyglucose-avid metastatic thyroid cancer lesions to treatment with high-dose radioactive iodine.
Thyroid
December 2001
Department of Radiology, The Laurent and Alberta Gerschel PET Center, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Radioactive iodine (131I) is an important therapeutic option for the treatment of metastatic thyroid carcinoma. Survival in patients with metastases that concentrate radioiodine is better than those whose metastatic lesions do not take up radioiodine. Survival is markedly reduced in patients who have metastatic lesions that concentrate 18F-fluorodeoxyglucose (FDG) on positron emission tomography (PET).
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