Objective: Stomahesive skin-protection powder has been reported to be useful as a skin-care and skin-barrier product for the management of stomas. This study aimed to evaluate its efficacy, in terms of wound healing, moisture retention and pain management, as an alternative to conventional dressing materials. Both clinical and animal studies were undertaken.
Method: The efficacy of the Stomahesive powder was tested by measuring the thickness of granulation tissue formed in a total skin defect in a db/db mouse model. We then compared the healing process using either the skin-protection powder or a conventional film dressing material. In the clinical study 17 patients with various intractable ulcers were treated with Stomahesive powder, and healing was evaluated.
Results: In the mouse model, granulation tissue in the wounds treated with the powder was 2.86 times thicker than that of the wounds treated with the film dressing. In the clinical study, 16 out of 17 wounds healed completely.
Conclusion: The Stomahesive powder could be an effective treatment modality for contact ulceration, superficial ulcers with complex contours and morphology, and superficial ulcers contaminated by liquid faeces or vaginal discharge that have not responded to conventional dressings.
Declaration Of Interest: None.
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http://dx.doi.org/10.12968/jowc.2006.15.10.26974 | DOI Listing |
Int J Biol Macromol
April 2024
Department of Food Science and Biotechnology, and Carbohydrate Bioproduct Research Center, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul 05006, Republic of Korea. Electronic address:
Glycogen is a naturally occurring or metabolically synthesized biological macromolecule found in a wide range of living organisms, including animals, microorganisms, and even plants. However, naturally sourced glycogen poses challenges for industrial use. This study focused on a biological macromolecule referred to as glycogen-like particles (GLPs), detailing the production methods and biological properties of these particles.
View Article and Find Full Text PDFJ Tissue Viability
May 2023
Nursing Division, Singapore General Hospital, Singapore. Electronic address:
Introduction: Incontinence-associated dermatitis (IAD) is a type of irritant contact dermatitis due to prolonged exposure of the skin to moisture induced by urine or/and faeces. The main principles when treating IAD involves protecting the skin from further exposure to irritants, establishing a healing environment, and eradicating skin infections. This study aimed to evaluate the effectiveness of the hydrocolloid crusting method (HCM) versus the standard care method (SCM) in treating IAD.
View Article and Find Full Text PDFInt J Nanomedicine
December 2022
College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Purpose: Orobol is an isoflavone that has a potent skin protection effect. The objective of this study was to prepare a novel bentonite-based composite formulation of orobol to enhance topical skin delivery.
Methods: The composition was optimized based on the orobol content in the composite and the in vitro release studies, followed by the in vitro and in vivo hairless mouse skin deposition studies.
J Biomed Mater Res A
March 2023
Chemical and Geological Sciences Department, University of Cagliari, Research Unit of the National Consortium of Materials Science and Technology (INSTM), Cittadella Universitaria di Monserrato, Monserrato, Italy.
An innovative nanotechnology-based approach was used for the preparation of Centella asiatica (C. asiatica) extract-SiO nanocomposites, specifically tailored for skin protection from oxidative damage. Different amounts of C.
View Article and Find Full Text PDFHeliyon
May 2021
Department of Environment, Faculty of Science, University of Kufa, Najaf Governorate, Iraq.
This study focuses to measure the emission of alpha particle rates (EAPR) and heavy metal concentrations (Cd, Pb, Zn, Cr, and Co) (HMC) in some cosmetics (kohl eye, compact powder, and lipsticks) from Najaf markets using CR39 Detectors and Spectrophotometry, respectively. The EAPR range from 0.0068 to 0.
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