AI Article Synopsis
- Xe-CT is a technique that measures regional lung ventilation by observing changes in attenuation during multiple breathing cycles while inhaling a set concentration of xenon.
- The study tested the effects of lower concentrations of xenon, including a mix with krypton, on determining how quickly the lungs respond (time constant) during imaging of anesthetized sheep.
- Results showed that while average time constants remained stable across different concentrations of xenon, a decrease in signal quality (higher variability and noise) was observed at lower concentrations, suggesting the xenon-krypton mixture could provide a reliable alternative for assessing lung ventilation in humans.
Article Abstract
Xenon computed tomography (Xe-CT) is used to estimate regional ventilation by measuring regional attenuation changes over multiple breaths while rebreathing a constant Xe concentration ([Xe]). Xe-CT has potential human applications, although anesthetic properties limit [Xe] to
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http://dx.doi.org/10.1152/japplphysiol.01235.2005 DOI Listing Publication Analysis
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