[Experimental study on the migration of vascular endothelial cells stimulated by IL-8].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi

Institute of Biomedical Engineering, West China Medical Center, Sichuan University, Chengdu 610041, China.

Published: October 2006

To investigate the influence of different concentrations of IL-8 on the migration of vascular endothelial cells and find out the best IL-8 concentration, the transwell chamber motility assay and the scrape motility assay were applied to observe the migration of vascular endothelial cells induced by IL-8. The results demonstrated that the migration of vascular endothelial cells was increased significantly under different IL-8 concentrations, while the best effect occurred when IL-8 concentration was 100 ng/ml.

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