Objective: To develop a new injectable biomaterial carrageenan/nano-hydroxyapatite/collagen (nHAC/Carr) for bone surgery and characterize it.
Methods: nHAC/Carr was developed by filling carrageenan with nano-hydroxyapatite/collagen (nHAC) granules.
Results: It was found that nHAC/Carr had similar X-ray diffraction patterns with that of nHAC. Fourier transform infrared spectroscopy showed that carrageenan did not change its structure in nHAC/Carr. The rheological behavior of nHAC/Carr was the same as carrageenan. The scanning electron microscopy and porosity analysis showed that nHAC/Carr had porous structure and its porosity was about 90%.
Conclusion: The biomaterial nHAC/Carr may be used as an injectable bone substitute.
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