Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Mitrofanoff complications: time-to-event analysis of split versus intact appendix and meta-analysis.
World J Urol
January 2025
Division of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Objectives: To assess the complication rates associated with split versus intact appendix Mitrofanoff procedures using a single-center retrospective analysis and a systematic review with meta-analysis.
Subjects And Methods: The study comprised a retrospective cohort analysis at a single institution, analyzing patients who underwent a laparoscopic-assisted Mitrofanoff with or without splitting the appendix from 2005 to 2016. The focus was on complications related to both Mitrofanoff and ACE channels.
A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance.
Dev Cell
January 2025
Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:
Distinguishing tumor maintenance genes from initiation, progression, and passenger genes is critical for developing effective therapies. We employed a functional genomic approach using the Lazy Piggy transposon to identify tumor maintenance genes in vivo and applied this to sonic hedgehog (SHH) medulloblastoma (MB). Combining Lazy Piggy screening in mice and transcriptomic profiling of human MB, we identified the voltage-gated potassium channel KCNB2 as a candidate maintenance driver.
View Article and Find Full Text PDFAn Effective Methodology for Diabetes Prediction in the Case of Class Imbalance.
Bioengineering (Basel)
January 2025
SP Jain Global School of Management, Academic City, Dubai P.O. Box 502345, United Arab Emirates.
Diabetes causes an increase in the level of blood sugar, which leads to damage to various parts of the human body. Diabetes data are used not only for providing a deeper understanding of the treatment mechanisms but also for predicting the probability that one might become sick. This paper proposes a novel methodology to perform classification in the case of heavy class imbalance, as observed in the PIMA diabetes dataset.
View Article and Find Full Text PDFStrains of a virtuoso: pacemaker infection and ventricular tachycardia in a violinist.
BMC Cardiovasc Disord
January 2025
Department of Hematology and Oncology, Shenzhen Children's Hospital of China Medical University, Shenzhen, 518038, China.
Purpose: Pacemaker-related infections are serious complications of cardiac implantable electronic devices (CIEDs). This case report aims to describe the occurrence of pacemaker pocket infection and recurrent ventricular tachycardia (VT) in a Chinese amateur violinist with sick sinus syndrome (SSS), and to explore the possible connection between occupational habits and the infection, as well as VT.
Methods: A 76-year-old male violinist with a Biotronik Evia DR dual-chamber pacemaker presented with syncope and signs of a pacemaker pocket infection three years after implantation.
Disseminated Cysticercosis.
Radiographics
February 2025
From the Department of Radiology, Hong Kong Children's Hospital, Kowloon Bay, Hong Kong (K.F.K.F.); Department of Diagnostic and Interventional Radiology, The Hospital for Sick Children, Toronto, Ontario, Canada (K.F.K.F.); Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Conn (I.D.d.O.S.); Department of Radiology, Division of Musculoskeletal and Intervention, University of Washington, Seattle, Wash (A.P.); Department of Radiology, Bai Jerbai Wadia Hospital for Children, Mumbai, India (F.G.); and Division of Body Imaging, Department of Radiology, University of Iowa Health Care, Iowa City, Iowa (Y.A.).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!