Human granulocytic anaplasmosis in northeastern Italy.

Ann N Y Acad Sci

Department of Infectious Disease, Via Colugna No. 50, 33100 Udine, Italy.

Published: October 2006

AI Article Synopsis

  • A study in northeastern Italy investigated the presence of human granulocytic anaplasmosis (HGA) and other tick-borne diseases (TBDs) in patients with recent tick bites.
  • Out of 79 patients, 30 (38%) were diagnosed with a TBD, including 24 with Lyme disease and 5 with human granulocytic ehrlichiosis (HGE).
  • The results suggest HGA is prevalent in the region, highlighting the need for doctors to consider HGA when diagnosing patients after a tick bite, especially due to the frequent co-infection with Lyme disease.

Article Abstract

Sporadic cases of human granulocytic anaplasmosis (HGA) have been reported in areas with a high prevalence of tick-borne diseases (TBDs) in Europe. We aimed at estimating the sero-prevalence of A. phagocytophilum and other TBDs in northeastern Italy in outpatients with a history of recent tick bite or suspected TBD. In the 1-year study, 79 patients were enrolled and 30 (38%) received a diagnosis of TBD: 24 (30%) with Lyme disease and 5 (6%) with HGE. Our findings indicate the presence of HGA in northeastern Italy; so, since co-infection with Lyme disease appeared to be frequent, physicians assessing patients after a tick bite should consider HGA in the diagnosis.

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http://dx.doi.org/10.1196/annals.1374.015DOI Listing

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