The toxicity to Photobacterium phosphoreum of different mixture systems of sodium dodecyl sulfate (SDS) and three substituted aromatic compounds according to equiconcentration ratio of 1 : 1, as well as individual toxicity, were determined respectively. The joint toxicity was evaluated by toxicity unit (TU), additive index (AI), similarity parameter (lambda), and mixtures toxicity index (MTI). Four evaluating methods were compared and the modes of joint action of different systems were analyzed primarily. The coherent results were obtained from four different evaluating methods. Conclusions can be drawn that the binary joint effects of phenol and toluene mixed with SDS showed weak synergistic, while the other joint effects of SDS and substituted aromatic compounds were antagonistic. Of the evaluating methods, Toxic Unit is most sensitive with higher value of its parameter. Mechanisms of joint toxicity action could be discussed according to luminescence principle of Photobacterium phosphoreum and molecule structures of the mixture components.
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Curr Med Chem
January 2025
Brazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Novel Radiopharmaceuticals and Nanoradiopharmacy, Rio de Janeiro, 21941906, Brazil.
This study discusses the chemical perspectives of the [18F]F-PSMA probe, a pivotal tool in prostate cancer imaging. [18F]Fluorine, a positron emitter with a half-life of 109.8 minutes, is produced in a cyclotron by bombarding [18O]-enriched targets with protons.
View Article and Find Full Text PDFNat Chem
January 2025
CCNU-uOttawa Joint Research Centre, Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China.
Nitroarenes are readily accessible bulk chemicals and can serve as versatile starting materials for a series of synthetic reactions. However, due to the inertness of the C-NO bond, the direct denitrative substitution reaction with unactivated nitroarenes remains challenging. Chemists rely on sequential reduction and diazotization followed by the Sandmeyer reaction or the nucleophilic aromatic substitution of activated nitroarenes to realize nitro group transformations.
View Article and Find Full Text PDFChemistry
January 2025
Beijing University of Posts and Telecommunications, School of Science, Beijing, CHINA.
Cofacial electron donor-acceptor dyads exhibiting through-space charge-transfer (TSCT) characteristics are widely employed in the development of optoelectronic functional materials. The flexible molecular frameworks between the electron donor and acceptor components allow dynamic modulation of electronic coupling, influenced by excited-state structural relaxation or intermolecular interactions, thereby affecting the charge-transfer (CT) dynamics and the emission properties of TSCT states. In this work, we examine the TSCT dynamic processes of two electron donor-acceptor dyads, CzPhNI and CzPhPI formed by ortho-substitution of phenyl linkage with V-shaped flexible TSCT structures using carbazole as donor and naphthalimide or phthalimide as acceptor.
View Article and Find Full Text PDFJ Mol Model
January 2025
Institute of Molecular Science, Shanxi University, Taiyuan, 030006, China.
Context: Inspired by the newly synthesized endohedral fullerene T CH@C (1) and based on extensive density functional theory calculations, we predict herein a series of endohedral borafullerenes C CH@BC (4), T BH@BC (5), C HO@BC (6), C NH@BC (7), and T C@BC (8) which possess a BC (3) shell isovalent with C, with the neutral D C@BC (9) obtained from C@BC (8) by symmetric C─B substitutions. Detailed adaptive natural density partitioning (AdNDP) bonding analyses and iso-chemical shielding surfaces (ICSSs) calculations indicate that these core-shell species are spherically aromatic in nature, rendering high stability to the systems. More interestingly, based on the calculated effective donor-acceptor interaction between LP(O) → LV(B@BC) in HO@BC (6), we propose the concept of boron bond (BB) in chemistry which is defined as the in-phase orbital overlap between an electronegative atom A as lone-pair (LP) donor and an electron-deficient boron atom with a lone vacant (LV) orbital as LP acceptor.
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January 2025
Departamento de Química, Instituto Tecnológico de Aeronáutica, São José dos Campos, Brazil.
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