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ASO Author Reflections: How to Control Hypothyroidism and Hypoparathyroidism Following Pharyngo-Laryngo-Esophagectomy for Cervical Esophageal Cancer.
Ann Surg Oncol
December 2021
Department of Surgery, School of Medicine, Keio University, Tokyo, Japan.
Thyroid and Parathyroid Functions After Pharyngo-Laryngo-Esophagectomy for Cervical Esophageal Cancer.
Ann Surg Oncol
October 2019
Department of Surgery, School of Medicine, Keio University, Tokyo, Japan.
Background: Cervical esophageal cancer (CEC) patients whose larynx function cannot be preserved often undergo chemoradiotherapy, whereas those with residual or recurrent lesions undergo a pharyngo-laryngo-esophagectomy (PLE); however, some need to undergo a pharyngolaryngectomy with total esophagectomy (PLTE) for synchronous or metachronous esophageal cancer. We retrospectively evaluated the relationship between preoperative irradiation (or the extent of esophageal resection) and postoperative endocrine complications in CEC, including hypothyroidism and hypoparathyroidism.
Methods: The cancers of 35 (5.
Current management of cervical esophageal cancer.
World J Surg
March 2011
Division of Esophageal and Upper Gastrointestinal Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, Hong Kong SAR.
Background: Pharyngo-laryngo-esophagectomy (PLE) has been regarded as a standard treatment for cervical esophageal cancer, but the morbidity and mortality rates associated with PLE are substantial. Chemoradiation (CTRT) is widely used to treat esophageal cancer; however, its role in managing cervical esophageal cancer has not been fully elucidated. It was hypothesized that up-front CTRT could be an effective alternative treatment option to PLE.
View Article and Find Full Text PDFThyroidectomy and hypoparathyroidism in patients with pharyngoesophageal tumors.
Head Neck
February 2006
Head and Neck Service, Department of Surgery, Faculty of Medical Sciences, State University of Campinas (Unicamp), Rua Roxo Moreira, No. 1234, Cidade Universitaria, 13083-591 Campinas, Sp Brazil.
Background: Total pharyngolaryngoesophagectomy and gastric transposition (TPLEGT) for pharyngoesophageal (PE) tumors may require thyroidectomy (with or without removal of the parathyroid glands) to obtain adequate margins around the tumor. As a result, a considerable number of patients may have hypoparathyroidism (HP) develop. The objective of this article is to report our experience with different types of thyroidectomy and to describe the relationship of thyroidectomy to HP in TPLETG.
View Article and Find Full Text PDFSurgical treatment of extensive hypopharyngeal carcinoma often includes total thyroidectomy together with resection of the primary disease. The risk of removing or damaging the parathyroid glands is considerable; this may render the patient permanently hypoparathyroid with all the problems of management. These patients must be on lifelong supplementation and at times, due to failure to take the medication, hypocalcemic crises are precipitated.
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