We have experienced three gastric cancer cases successfully treated by the combination therapy of CDDP and TS-1. Case 1: 65-year-old man, a type 4 gastric cancer with huge abdominal para-aortic lymphnodes. Case 2: 74-year-old woman, a type 3 gastric cancer was found with obstructive jaundice. Swelling lymph nodes were seen in the hepatoduodenal ligament. Case 3: 58-year-old woman, a type 4 gastric cancer was found. The tumor invading the pancreas and swelling lymphnodes around the stomach were confirmed according to abdominal CT. Although combined chemotherapy of TS-1 plus CDDP is effective for advanced gastric cancer,adjuvant-chemotherapy must be investigated in noneffective cases.
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