Over a 10 year period, 530 patients were treated at the Lille Laser Center for a rectosigmoid tumour. Both argon and Nd:YAG lasers were used. Two hundred patients were treated for palliation of symptoms from a rectosigmoid cancer, 313 patients were treated for a rectosigmoid villous adenoma, and 17 patients with a familial polyposis were treated for the rectal polyposis remaining after total colectomy. The immediate success rate and complication rate were 88% and 2.7%, respectively, for patients with advanced cancer, 92% and 2% for those with a villous adenoma, and 100% and 0% for those with polyposis. Patients with an advanced cancer remained functionally improved during a 10.1 month average period after initial improvement. The recurrence rate after initial treatment for villous adenomas was 14% during a 3.1 year average follow-up. Immediate results were influenced by reason for treatment, initial symptoms and circumferential extension for patients with a cancer, and only by circumferential extension for patients with a villous adenoma. Long term results were influenced by reason for treatment and circumferential extension for patients with a cancer, and by reason for treatment, initial histology and localization for patients with a villous adenoma.
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J Gastrointest Oncol
December 2024
Department of Internal Medicine, HCA Healthcare/USF Morsani College of Medicine GME, HCA Florida Blake Hospital, Bradenton, FL, USA.
Background: Colorectal cancer (CRC) causes substantial morbidity and mortality internationally. In Hungary, the incidence and mortality of CRC are among the world's highest. Fortunately, CRC is a highly preventable disease, since there is a long asymptomatic phase before neoplastic transformation.
View Article and Find Full Text PDFJ Med Case Rep
January 2025
Department of Surgery, University Hospital "Tsaritsa Joanna - ISUL", Medical University, Str. "Byalo More" No 8, Sofia, Bulgaria.
Background: McKittrick-Wheelock syndrome is an uncommon and severe disorder caused by large hypersecretory tumors located in the distal colorectal area. Excessive secretion from adenomas is an unusual clinical manifestation that leads to severe electrolyte and fluid depletion, subsequently resulting in kidney injury. Successful treatment relies on quick and cooperative decision-making for timely intervention.
View Article and Find Full Text PDFAm J Gastroenterol
December 2024
Division of Environmental Health Sciences, University of Minnesota, Minneapolis, Minnesota, USA.
Introduction: Despite reports indicating that polyps proximal to the splenic flexure have higher rates of metachronous colorectal adenocarcinoma (CRC), the role of adenoma location on surveillance recommendations remains unclear. This study aimed to analyze the association between index polyp location and postcolonoscopy CRC among participants of the Minnesota Colon Cancer Control Study.
Methods: The Minnesota Colon Cancer Control Study randomized 46,551 patients 50-80 years to usual care, annual, or biennial screening with fecal occult-blood testing.
Cureus
October 2024
Gastroenterology, Faculdade de Medicina, Universidade de Sao Paulo, Serviço de Endoscopia Gastrointestinal do Hospital das Clínicas, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, BRA.
Traditional serrated adenomas (TSAs) of the duodenum are rare lesions with potential for malignant transformation. We present the case of a 44-year-old female with a history of bariatric surgery who presented with worsening abdominal pain, nausea, and significant weight loss. Imaging studies, including MRI, revealed a 3.
View Article and Find Full Text PDFCureus
October 2024
Gastroenterology, Macclesfield District General Hospital, Macclesfield, GBR.
Background Colorectal cancer (CRC) remains a significant public health challenge. Patients having abnormal faecal immunochemical test (FIT) results are offered a colonoscopy. The effectiveness of colonoscopies can, however, often be challenged by the occurrence of missed polyps.
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