AI Article Synopsis

  • A fatal case of legionellosis in Calgary led to an investigation of the infection's source, highlighting the risks posed by contaminated hospital water systems to vulnerable patients.
  • The Legionella pneumophila strain found in the patient was matched to a persistent strain in the hospital water, confirming it was contracted within the hospital.
  • Unique genetic patterns were identified for unrelated cases and isolates from other hospitals, emphasizing the importance of tracking bacterial strains in healthcare settings.

Article Abstract

A fatal case of nosocomial legionellosis in a low prevalence region (Calgary, Alberta, Canada) prompted investigation into the source of infection. Hospital water systems contaminated with Legionella pneumophila have been shown to pose a risk to compromised patients. Typing of an L. pneumophila serogroup 1 strain isolated from the patient using sequence-based typing (SBT) and amplified fragment length polymorphism (AFLP) analysis linked it to a persistent and widespread strain isolated from the hospital water system establishing a nosocomial mode of acquisition. Different SBT and AFLP patterns were determined for non-epidemiologically linked cases and isolates from different hospitals.

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http://dx.doi.org/10.1099/jmm.0.46754-0DOI Listing

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