Objective: To present data of cases with choanal atresia (CA) from Saudi patients, and to compare them to the data from the international literature.
Methods: A retrospective analysis of the data available from the files of 37 consecutive patients with the diagnosis of CA at King Abdul-Aziz University Hospital, Riyadh, Kingdom of Saudi Arabia between January 1999 and December 2005. This involved reviewing the age, gender, presenting symptoms, associated anomalies, surgical intervention, and outcomes.
Results: Twenty-three of our cases had unilateral and 14 had bilateral CA. Strikingly, 83% of unilateral CA involved the right side. In our study, we found the female to male ratio to be 2:1. Approximately, 95% of the cases had mixed bony and membranous CA. Thirty-two percent of the cases had other associated congenital anomalies. Most of our cases had their surgical intervention by endoscopic technique.
Conclusion: Choanal atresia is a rare anomaly. In Saudi children, female is more commonly affected than male. There is a striking rate of involvement of the right side in the cases of unilateral CA.
Download full-text PDF |
Source |
---|
Cureus
December 2024
Family Medicine, Louisiana State University Health Sciences Center, Alexandria, USA.
The VACTERL (vertebral defects, anal atresia, cardiac defects, tracheoesophageal fistula, renal anomalies, and limb abnormalities) association represents an enigmatic syndrome requiring further study. This report describes a full-term neonate born to a multiparous woman who was found, upon further examination, to have multiple congenital abnormalities, including a bicuspid aortic valve, patent foramen ovale, tracheoesophageal fistula (TEF), asymmetric crying facies, microphallus, and a single inguinal testis. The discussion explores environmental and genetic factors that may contribute to this association, as well as similar conditions, such as CHARGE (coloboma, heart defects, choanal atresia, growth retardation, genital abnormalities, and ear abnormalities) syndrome.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
January 2025
Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:
Objectives: Surgery is the only treatment for congenital choanal atresia (CCA). It is crucial to avoid postoperative restenosis or re-occlusion of the neo-choana. This study investigated the efficacy of a navigation-assisted endoscopic endonasal U-flap technique and a bioabsorbable steroid-eluting stent for CCA repair.
View Article and Find Full Text PDFJ Rhinol
November 2024
Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Background And Objectives: Congenital choanal atresia is a rare condition that occurs in approximately 1 in 7,000 to 8,000 live births and involves the obstruction of the posterior nasal airway. It may present as either unilateral or bilateral, with bilateral cases being more severe due to the risk of immediate neonatal respiratory distress. Bilateral congenital choanal atresia (BCCA) necessitates prompt medical intervention to prevent cyanosis and significant breathing difficulties.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
November 2024
This article reports a case of congenital choanal atresia with additional nostril and nasal deformities admitted to Henan Children's Hospital. A 43-day-old female patient was admitted to the hospital because of wheezing with mouth opening breathing and restricted feeding after birth'. The patient was diagnosis as bilateral congenital posterior nostril membranous atresia, congenital extra nostril nasal deformity and nasal stenosis by fiberoptic nasopharyngoscopy, CT, gene detection, and physical examination results.
View Article and Find Full Text PDFCureus
October 2024
Genetics, Prince Sultan Military Medical City, Riyadh, SAU.
Desanto-Shinawi syndrome (DESSHS) is a rare autosomal dominant disorder caused by a loss of function variant or deletion of the WAC gene. DESSHS is characterized by dysmorphic features and global developmental delay. In this report, we discuss three boys with DESSHS.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!