Purpose: Infantile nystagmus (IN) has been reported to decrease with convergence. However, previous studies reported equivocal results regarding a corresponding improvement in acuity with near viewing. The aim of this study was to determine whether visual acuity improves with near viewing in patients with IN.
Methods: In the first experiment, visual acuities were measured using clinical test charts at standard test distances of 3 or 6 m and 40 cm and using S Charts at 3.75 m and 40 cm. In the second experiment, visual acuities were measured using a Bailey-Lovie chart at distance and a Lighthouse modified ETDRS near card held by each subject at his or her preferred working distance. S-chart acuities were obtained again at 3.75 m and 40 cm for comparison. Horizontal eye movements were recorded using infrared limbal reflection for 20 of the 34 subjects in the first experiment and for all 20 subjects in the second experiment.
Results: The S-chart acuities measured at distance and near were almost all within 0.1 logMAR (logarithm of the minimum angle of resolution) in experiments 1 and 2. Clinically measured acuity averaged nearly one line better at 40 cm than at distance in experiment 1, but the mean difference between near acuity using the ETDRS card and distance acuity using the Bailey-Lovie chart was less than one letter in experiment 2. No consistent relationship existed between the changes in visual acuity with viewing distance and the subject's eye movements.
Conclusion: Despite a reduction of nystagmus at near distances in many patients with IN, the visual acuity at near does not improve significantly. These results imply that visual acuity in patients with IN is determined primarily by sensory limitations rather than by the moment-by-moment characteristics of these patients' eye movements.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/01.opx.0000238650.33150.73 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Analysis of quantitative OCT and SS-OCTA metrics three months after initiation of intravitreal faricimab for treatment-recalcitrant neovascular AMD.
Eye (Lond)
January 2025
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Purpose: To utilize optical coherence tomography (OCT) and SS-OCT angiography (SS-OCTA) for quantifying morphological changes seen in eyes with recalcitrant neovascular age-related macular degeneration (nAMD) transitioned to intravitreal faricimab injections during the manufacturer's recommended induction phase of treatment.
Methods: Fifty-four treatment-recalcitrant patients (60 eyes) were recruited. OCT and SS-OCTA images were obtained at 0 and 3 months.
1-Year real-world outcomes of faricimab in previously treated neovascular age-related macular degeneration.
Eye (Lond)
January 2025
Maidstone Hospital Eye Department, Hermitage Lane, Maidstone, UK.
Background And Objectives: Faricimab, a bispecific antibody targeting VEGF-A and angiopoietin-2, has shown promise in treating neovascular age-related macular degeneration (nAMD). This study evaluates 1-year outcomes of faricimab in treatment-experienced nAMD patients.
Methods: This single-centre retrospective cohort study included patients previously treated for nAMD who switched to faricimab between November 2022 and March 2024.
Poor fixation stability does not account for motion perception deficits in amblyopia.
Sci Rep
January 2025
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
People with amblyopia show deficits in global motion perception, especially at slow speeds. These observers are also known to have unstable fixation when viewing stationary fixation targets, relative to healthy controls. It is possible that poor fixation stability during motion viewing interferes with the fidelity of the input to motion-sensitive neurons in visual cortex.
View Article and Find Full Text PDFClinical features, diagnosis, management, and prognosis of circumscribed choroidal hemangioma.
Surv Ophthalmol
January 2025
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China; Key Lab of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address:
Because of its benign nature and rarity, circumscribed choroidal hemangioma (CCH) often receives limited attention, leading to a high rate of misdiagnosis and a lack of standardized treatment protocols. We provide a thorough clarification of the demographics, clinical features, diagnosis, management, and prognosis of CCH. We conducted a systematic search of the PubMed, EMBASE, and Ovid databases up to December, 2023, to identify relevant studies.
View Article and Find Full Text PDFVisual Acuity Outcomes and Influencing Factors in a Cohort of UK Real-World Diabetic Macular Oedema Patients During the First Two Years of Anti-VEGF Treatment.
Pharmaceutics
January 2025
Centre for Public Health, Institute of Clinical Sciences, School of Medicine, Queen's University Belfast, Belfast BT7 1NN, UK.
Background/objectives: The visual acuity (VA) outcomes after the first and second years of anti-vascular endothelial growth factor (anti-VEGF) treatment in patients with diabetic macular oedema (DMO) were evaluated, and the factors associated with treatment success were investigated.
Methods: Using Medisoft electronic medical records (UK), this retrospective cohort study analysed VA outcomes, changes, and determinants in DMO patients at year 1 and year 2 after initial anti-VEGF injection. Descriptive analysis examined baseline demographics and clinical characteristics, while regression models were used to assess associations between these factors and changes in VA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!