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Control of salivary secretions in esophageal atresia with laryngeal cleft using Botulinum toxin Type A.
Int J Pediatr Otorhinolaryngol
July 2008
Department of Ear, Nose & Throat Surgery, The Sheffield Children's Hospital, Western Bank, Sheffield, South Yorkshire, UK.
A baby born with esophageal atresia and a laryngeal cleft is presented. Retained salivary secretions and aspiration were a constant management problem whilst the baby was waiting for delayed primary repair of the atresia. The use of anticholinergic agents resulted in thickening of secretions which were difficult to suction and ultimately led to increasing respiratory compromise.
View Article and Find Full Text PDFBovine pituitary intraglandular colloid fraction F5 localized in the rat endocrine pancreas.
Experientia
January 1985
Bovine pituitary intraglandular colloid thought to be a waste product, is the holocrine secretion of intermediate lobe cells. It is housed in the intraglandular lumen (residual lumen) and is extruded into the venous circulation of the cavernous sinuses via clefts in the capsule of the gland aligned with the intraglandular lumen. Intraglandular colloid, fraction F5 (mol.
View Article and Find Full Text PDFIn bovine, the intermediate lobe is highly active and the holocrine secretion of its marginal cell layer forms a colloid-like substance housed in the intra-glandular cleft (residual lumen). Immunodiffusion of fractions of intraglandular colloid shows determinants sharing antigenic specificity with GH, FSH, CSF and serum immunoglobulins. The fractions tested by PAGE show determinants common to intraglandular colloid, CSF and serum albumin.
View Article and Find Full Text PDFThe relationship of intraglandular colloid production to hormone synthesis.
Experientia
September 1980
The production of intraglandular colloid, brought about by the cyclic breakdown of intermediate lobe cells, is related to the synthesis of hormones in the hypophysis. By analyzing the 'shift' of the amino acid, cystine, during various phases of the gland's cycle it is apparent that hormones, as well as other protein determinants of immunological importance, are transported by way of the intraglandular cleft to the venous circulation and to the cerebrospinal fluid.
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