AI Article Synopsis
- Jaundice occurs in about 2.5% of patients with severe malaria, particularly in those with falciparum infections, but significant liver issues like hepatitis are rare.
- Cases of liver dysfunction in malaria are rising globally, ranging from mild liver function test abnormalities to severe liver failure.
- Early recognition and proper management of hepatic dysfunction in malaria can lead to better outcomes, so it's crucial for healthcare providers to monitor liver health closely in these patients and differentiate it from more severe liver conditions.
Article Abstract
Jaundice is a common clinical presentation in severe malaria, seen in approximately 2.5% patients with falciparum infection but hepatitis is unusual. Although hepatic dysfunction is unusual and hepatic encephalopathy is almost never seen in malaria, yet, cases of hepatic dysfunction are being increasingly reported in patients with P.falciparum infection, from different parts of world. The extent of hepatocellular dysfunction varies from mild abnormalities in liver function tests to hepatic failure. Patients with hepatocellular dysfunction in malaria are more prone to develop complications, but have a favorable outcome if hepatic involvement is recognized early and managed properly. It is important to meticulously look for hepatic dysfunction in patients with severe malaria, distinguish it from fulminant hepatic failure and manage it aggressively.
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